苯甲基2-甲基哌啶-1,2-二羧酸酯 | 719277-25-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: 苯甲基2-甲基哌啶-1,2-二羧酸酯
• 中文别名: (1Z)-1-(3-乙基-5-甲基-1,3-苯并噻唑-2(3H)-亚基)丙酮
• 英文名称: (1Z)-1-(3-Ethyl-5-methyl-2(3H)-benzothiazolylidene)-2-propanone
• 英文别名: (1Z)-1-(3-ethyl-5-methyl-1,3-benzothiazol-2-ylidene)propan-2-one
• CAS: 719277-25-5
• 化学式: C₁₃H₁₅NOS
• 分子量: 233.33
• InChiKey: RJPPCEQRPIGQBN-JYRVWZFOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  45.6
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• PAIN-RELATED COMPOUND AND MEDICAL COMPOSITION
  申请人：KYOTO UNIVERSITY

  公开号：US20170029389A1

  公开（公告）日：2017-02-02

  Provided is a pain-related compound, a pain-related pharmaceutical composition, and use of the same. Provided in one or more embodiments is a compound represented by Formula (I), a prodrug of the same, or a pharmaceutically permissible salt of any of the same.

  提供了一种与疼痛有关的化合物、与疼痛有关的药物组合物及其使用。在一种或多种实施例中，提供了一种由公式（I）表示的化合物，其前药，或任何其中的药用允许的盐。
• US20140275064A1
  申请人：——

  公开号：US20140275064A1

  公开（公告）日：2014-09-18
• PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD FOR GENETIC DISEASE ASSOCIATED WITH SPLICING ABNORMALITIES
  申请人：KYOTO UNIVERSITY

  公开号：US20200113907A1

  公开（公告）日：2020-04-16

  A pharmaceutical composition for genetic diseases caused by an aberrant splicing regulation is provided. Provided are a pharmaceutical composition for preventing, ameliorating, suppressing progression of, and/or treating the genetic diseases caused by an aberrant splicing regulation, the pharmaceutical composition containing, as an active ingredient, a compound capable of suppressing an aberrant splicing regulation that contributes to the development or progression of genetic diseases caused by an aberrant splicing regulation, and a method for preventing, ameliorating, suppressing progression of, and/or treating the genetic diseases using a compound capable of suppressing an aberrant splicing regulation that contributes to the development or progression of genetic diseases caused by an aberrant splicing regulation.
• US9446044B2
  申请人：——

  公开号：US9446044B2

  公开（公告）日：2016-09-20
• US9745275B2
  申请人：——

  公开号：US9745275B2

  公开（公告）日：2017-08-29