1-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]propan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]propan-2-one
• 化学式: C₁₃H₁₆N₂O₂
• 分子量: 232.28
• InChiKey: JCFFHWDLULGCQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  68.1
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• USE OF N-ACETYL-5-METHOXYTRYPTAMINE OR ANALOGUES THEREOF, FOR PROMOTING THE MECHANISM OF IMPLANTATION OF THE EMBRYO AND RELATED COMPOSITIONS AND CULTURE MEDIA
  申请人：Ares Trading SA

  公开号：EP2854790A1

  公开（公告）日：2015-04-08
• [EN] USE OF N-ACETYL-5-METHOXYTRYPTAMINE OR ANALOGUES THEREOF, FOR PROMOTING THE MECHANISM OF IMPLANTATION OF THE EMBRYO AND RELATED COMPOSITIONS AND CULTURE MEDIA<br/>[FR] UTILISATION DE N-ACÉTYL-5-MÉTHOXYTRYPTAMINE OU D'ANALOGUES DE CELLE-CI POUR FAVORISER LE MÉCANISME D'IMPLANTATION DE L'EMBRYON ET COMPOSITIONS ET MILIEUX DE CULTURE S'Y RAPPORTANT
  申请人：MAXIA NICOLETTA

  公开号：WO2013178587A1

  公开（公告）日：2013-12-05

  The present invention refers to the use of N-acetyl-5-methoxytryptamine (melatonin) and/or an analogue thereof, for use in the medical or veterinary field in the assisted reproduction for promoting the mechanism of implantation of the embryo, and in particular for the prevention of implantation failure into the uterus, by topical administration of an effective amount in a mammalian subject female in need of such treatment, and related compositions, culture media and medical devices.