5-溴-2-甲氧基异氰酸苯乙酯 | 480439-04-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 5-溴-2-甲氧基异氰酸苯乙酯
• 中文别名: 5-溴-2-甲氧基苯乙基异氰酸酯
• 英文名称: 5-Bromo-2-methoxyphenethyl isocyanate
• 英文别名: 4-bromo-2-(2-isocyanatoethyl)-1-methoxybenzene
• CAS: 480439-04-1
• 化学式: C₁₀H₁₀BrNO₂
• 分子量: 256.1
• InChiKey: IEKFZVSKEVFNQZ-UHFFFAOYSA-N

物化性质

• 沸点：
  280-281 °C(lit.)
• 密度：
  1.454 g/mL at 25 °C(lit.)
• 闪点：
  >230 °F

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 危险品标志：
  Xn
• 海关编码：
  2929109000

文献信息

• COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES
  申请人：Vasudevan Anil

  公开号：US20100035919A1

  公开（公告）日：2010-02-11

  Disclosed herein are compounds of formula (I) or pharmaceutical acceptable salts thereof, wherein A, X 1 , X 2 , R 1 , R 2 , R 3 , m, n, and p are defined in the specification. Compositions including the compounds which can be useful for inhibiting Rho kinase (ROCK) and methods for using the compositions are also described.

  本文披露了式（I）的化合物或其药用可接受的盐，其中A、X1、X2、R1、R2、R3、m、n和p在规范中有定义。还描述了包括这些化合物的组合物，这些组合物可用于抑制Rho激酶（ROCK），并描述了使用这些组合物的方法。
• BENEFIT AGENT DELIVERY COMPOSITIONS
  申请人：The Procter and Gamble Company

  公开号：EP2111443A2

  公开（公告）日：2009-10-28
• Benefit agent delivery compositions
  申请人：Smets Johan

  公开号：US20080200363A1

  公开（公告）日：2008-08-21

  Benefit agent delivery compositions, compositions, packaged products and displays comprising such benefit agent delivery compositions, and processes for making and using such benefit agent delivery compositions, compositions, packaged products and displays. Such compositions have improved deposition and retention properties that may impart improved benefit characteristics to a composition and/or situs.
• [EN] BENEFIT AGENT DELIVERY COMPOSITIONS<br/>[FR] COMPOSITIONS D'ADMINISTRATION D'AGENT BÉNÉFIQUE
  申请人：PROCTER & GAMBLE

  公开号：WO2008100601A2

  公开（公告）日：2008-08-21

  [EN] Benefit agent delivery compositions, compositions, packaged products and displays comprising such benefit agent delivery compositions, and processes for making and using such benefit agent delivery compositions, compositions, packaged products and displays. Such compositions have improved deposition and retention properties that may impart improved benefit characteristics to a composition and/or situs.
  [FR] L'invention concerne des compositions d'administration d'agent bénéfique, des compositions, des produits et des dispositifs d'affichage conditionnés comprenant de telles compositions d'administration d'agent bénéfique, et des procédés de fabrication et d'utilisation de telles compositions d'administration d'agent bénéfique, de telles compositions, et de tels produits et dispositifs d'affichage conditionnés. De telles compositions ont amélioré les propriétés de dépôt et de conservation qui peuvent conférer des caractéristiques bénéfiques améliorées à une composition et/ou à un site.
• [EN] COMPOUNDS USEFUL AS INHIBITORS OF PROTEIN KINASES<br/>[FR] COMPOSÉS UTILES COMME INHIBITEURS DE PROTÉINE KINASES
  申请人：ABBOTT LAB

  公开号：WO2010017150A1

  公开（公告）日：2010-02-11

  Disclosed herein are compounds of formula (I) or pharmaceutical acceptable salts thereof, wherein A, X1, X2, R1, R2, R3, m, n, and p are defined in the specification. Compositions including the compounds which can be useful for inhibiting Rho kinase (ROCK) and methods for using the compositions are also described.