[(6S,7S,8aS)-7-azido-2-phenyl-6-phenylsulfanyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] benzoate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃二恶英
• 英文名称: [(6S,7S,8aS)-7-azido-2-phenyl-6-phenylsulfanyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-8-yl] benzoate
• 化学式: C26H23N3O5S
• 分子量: 489.5
• InChiKey: JNNVTQCCFRVRRA-DPCMRECBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  35
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  93.6
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• [EN] SYNTHETIC OLIGOSACCHARIDES FOR P. AERUGINOSA VACCINE<br/>[FR] OLIGOSACCHARIDES SYNTHÉTIQUES POUR VACCIN ANTI-P. AERUGINOSA
  申请人：ANCORA PHARMACEUTICALS INC

  公开号：WO2014014670A1

  公开（公告）日：2014-01-23

  The present invention provides synthetic Pseudomonasaeruginosa lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various P. aeruginosa serotype-specific oligosaccharide antigens or various core P. aeruginosa oligosaccharide structures or motifs. The invention further provides P. aeruginosa LOS-based immunogenic and immunoprotective compositions and antibodies derived therefrom for diagnosing, treating, and preventing infections caused by P. aeruginosa.