5-(azetidin-3-yloxy)-2,3-dihydro-1H-indole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5-(azetidin-3-yloxy)-2,3-dihydro-1H-indole
• 化学式: C₁₁H₁₄N₂O
• 分子量: 190.24
• InChiKey: XCCZFRRJUHPWPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  33.3
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS<br/>[FR] COMPOSÉS POUR LE TRAITEMENT DE TROUBLES NEUROLOGIQUES
  申请人：NEUROP INC

  公开号：WO2013170072A2

  公开（公告）日：2013-11-14

  In one aspect, the invention relates to NMDA receptor modulators, derivatives thereof, and related compounds, which are useful as inhibitors of the NMDA receptor; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating or preventing neurological and psychiatric disorders associated with NMDA receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.