(2S)-3-(1H-indol-3-yl)-2-(methylideneamino)propanal

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (2S)-3-(1H-indol-3-yl)-2-(methylideneamino)propanal
• 化学式: C₁₂H₁₂N₂O
• 分子量: 200.24
• InChiKey: VLUYPYGKGWISAZ-JTQLQIEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  45.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• OPTIMIZED MESSENGER RNA
  申请人：Selden Richard F.

  公开号：US20140350089A1

  公开（公告）日：2014-11-27

  The present invention is directed to a synthetic nucleic acid sequence which encodes a protein wherein at least one non-common codon or less-common codon is replaced by a common codon. The synthetic nucleic acid sequence can include a continuous stretch of at least 90 codons all of which are common codons.
• US8865448B2
  申请人：——

  公开号：US8865448B2

  公开（公告）日：2014-10-21
• US8969371B1
  申请人：——

  公开号：US8969371B1

  公开（公告）日：2015-03-03
• US9476054B2
  申请人：——

  公开号：US9476054B2

  公开（公告）日：2016-10-25
• [EN] COMPOSITIONS AND SYSTEMS FOR CONFERRING DISEASE RESISTANCE IN PLANTS AND METHODS OF USE THEREOF<br/>[FR] COMPOSITIONS ET SYSTÈMES POUR CONFÉRER UNE RÉSISTANCE À UNE MALADIE À DES PLANTES ET LEURS PROCÉDÉS D'UTILISATION
  申请人：UNIV INDIANA RES & TECH CORP

  公开号：WO2014042923A1

  公开（公告）日：2014-03-20

  Compositions, systems and methods are provided for conferring disease resistance to plant pathogens that use proteases to target plant substrate proteins inside plant cells. Briefly, the compositions, systems and methods are based upon plant substrate proteins that are targeted by pathogen-specific proteases and that activate nucleotide binding site-leucine rich repeat (NB-LRR) disease resistance proteins when cleaved by the protease. These substrate proteins are modified such that the endogenous protease recognition sequence is replaced by a protease recognition sequence specific to a different pathogen protease (i.e., a heterologous protease recognition sequence). The modified plant substrate protein therefore can be used in connection with its corresponding NB-LRR protein to activate resistance in response to cleavage by the heterologous pathogen-specific protease. When activated by the plant pathogen-specific protease, the pair initiates host defense responses thereto, including programmed cell death.