Cyclohexane-1,1-dicarboxylic acid;1-[2-(2-hydroxyoctadecylamino)ethylamino]octadecan-2-ol

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Cyclohexane-1,1-dicarboxylic acid;1-[2-(2-hydroxyoctadecylamino)ethylamino]octadecan-2-ol
• 英文别名: cyclohexane-1,1-dicarboxylic acid;1-[2-(2-hydroxyoctadecylamino)ethylamino]octadecan-2-ol
• 化学式: C46H92N2O6
• 分子量: 769.2
• InChiKey: IFIDABXTNUEBMB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.74
• 重原子数：
  54
• 可旋转键数：
  39
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  139
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• IMPLANTABLE MEDICAL DEVICE MADE FROM AN AMORPHOUS OR VERY LOW CRYSTALLINITY POLYMER CONSTRUCT
  申请人：Abbott Cardiovascular Systems Inc.

  公开号：US20140084515A1

  公开（公告）日：2014-03-27

  Methods of fabricating a polymeric implantable device with improved fracture toughness through annealing, nucleating agents, or both are disclosed herein. A polymeric construct that is completely amorphous or that has a very low crystallinity is annealed with no or substantially no crystal growth to increase nucleation density. Alternatively, the polymer construct includes nucleating agent. The crystallinity of the polymer construct is increased with a high nucleation density through an increase in temperature, deformation, or both. An implantable medical device, such as a stent, can be fabricated from the polymer construct after the increase in crystallinity.