(E)-6-[2-N,N-diethylaminovinyl]-7-chloro-pyrimido[1,2-a]benzimidazole-8,9-dione | 1448998-69-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并[1，2-a]嘧啶
• 英文名称: (E)-6-[2-N,N-diethylaminovinyl]-7-chloro-pyrimido[1,2-a]benzimidazole-8,9-dione
• 英文别名: 8-chloro-9-[(E)-2-(diethylamino)ethenyl]pyrimido[1,2-a]benzimidazole-6,7-dione
• CAS: 1448998-69-3
• 化学式: C₁₆H₁₅ClN₄O₂
• 分子量: 330.774
• InChiKey: QSCRTITZSQJZPI-RMKNXTFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  67.6
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  6,7-dichloropyrimido[1,2-a]benzimidazole-8,9-dione 、 乙醛 、 二乙胺 以 二氯甲烷 为溶剂， 反应 0.5h， 以12%的产率得到(E)-6-[2-N,N-diethylaminovinyl]-7-chloro-pyrimido[1,2-a]benzimidazole-8,9-dione
  参考文献：
  名称：

  Synthesis of 6,7-dichloropyrido[1,2-a]benzimidazole-8,9-dione and its analogues and their reactions with nucleophiles

  摘要：

  Novel 6,7-dichloropyrido[1,2-a]benzimidazole-8,9-dione derivatives and its analogues were synthesized directly from chloranil and different 2-amino(di)azines without using a catalyst or activation. Further nucleophilic substitution reactions were carried out. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.06.094

文献信息

• Synthesis of 6,7-dichloropyrido[1,2-a]benzimidazole-8,9-dione and its analogues and their reactions with nucleophiles
  作者：Nelli Batenko、Sergey Belyakov、Glebs Kiselovs、Raimonds Valters

  DOI：10.1016/j.tetlet.2013.06.094

  日期：2013.8

  Novel 6,7-dichloropyrido[1,2-a]benzimidazole-8,9-dione derivatives and its analogues were synthesized directly from chloranil and different 2-amino(di)azines without using a catalyst or activation. Further nucleophilic substitution reactions were carried out. (C) 2013 Elsevier Ltd. All rights reserved.