3-(3-Hydroxypropyl)-5-oxohexanoic acid;hydrate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: 3-(3-Hydroxypropyl)-5-oxohexanoic acid;hydrate
• 英文别名: 3-(3-hydroxypropyl)-5-oxohexanoic acid;hydrate
• 化学式: C9H18O5
• 分子量: 206.24
• InChiKey: DAUSRWUIUJQPOB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.0
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  75.6
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Process for producing monosaccharides
  申请人：JENNEWEIN BIOTECHNOLOGIE GMBH

  公开号：US20150240277A1

  公开（公告）日：2015-08-27

  The present invention relates to a process for producing a monosaccharide using a microorganism. The microorganism possesses a glycosyltransferase and a glycosidase which work together to synthesize a desired monosaccharide in free form by using an endogenous provided nucleotide activated monosaccharide, glycosylate a suitable acceptor substrate and release the desired monosaccharide by a hydrolysis reaction. The required acceptor substrate for the reaction is recycled and only needed in catalytic amounts. The monosaccharide is produced in free from and is retrieved from the supernatant of the cultivated microorganism.

  本发明涉及一种利用微生物生产单糖的方法。该微生物具有一种糖基转移酶和一种糖苷酶，二者共同作用，利用内源提供的核苷酸活化单糖，对适当的受体底物进行糖基化，并通过水解反应释放所需的单糖。反应所需的受体底物可以循环利用，只需少量催化即可。单糖以自由形式产生，并从培养的微生物上清液中提取。
• FUCOSYLTRANSFERASES AND THEIR USE IN PRODUCING FUCOSYLATED OLIGOSACCHARIDES
  申请人：Jennewein Biotechnologie GmbH

  公开号：EP3425052A1

  公开（公告）日：2019-01-09

  Disclosed are novel fucosyl transferases being capable of transferring a fucose residue from a donor substrate to a lactotetraose, methods for producing fucosylated oligosaccharides utilizing said fucosyl transferases, and the use of the thus produced fucosylated oligosaccharides for manufacturing nutritional compositions.

  本发明公开了能够将供体底物上的岩藻糖残基转移到乳四糖上的新型岩藻糖转移酶、利用所述岩藻糖转移酶生产岩藻糖化低聚糖的方法，以及利用由此生产的岩藻糖化低聚糖制造营养组合物。
• SIALYLTRANSFERASES FOR THE PRODUCTION OF 6'-SIALYLLACTOSE
  申请人：Jennewein Biotechnologie GmbH

  公开号：EP3772539A1

  公开（公告）日：2021-02-10

  Disclosed are enzymes, compositions, genetically engineered cells and methods for the fermentative production of 6'-sialyllactose.

  所公开的是发酵生产 6'-sialyllactose 的酶、组合物、基因工程细胞和方法。
• EP2728009A1
  申请人：——

  公开号：EP2728009A1

  公开（公告）日：2014-05-07
• FERMENTATIVE PRODUCTION OF SIALYLATED SACCHARIDES
  申请人：Jennewein Biotechnologie GmbH

  公开号：US20210198709A1

  公开（公告）日：2021-07-01

  Disclosed are methods for the fermentative production of a sialylated saccharide and genetically engineered microbial cells for use in said method, wherein the genetically engineered microbial cells comprise (i) a sialic acid biosynthesis pathway comprising a glucosamine-6-phosphate N-acetyltransferase, (ii) a cytidine 5′-monophospho-(CMP)-N-acetylneuraminic acid synthetase; and (iii) a sialyltransferase, for producing sialylated saccharides, as well as the use of said sialylated oligosaccharides for providing nutritional compositions.