ethyl 2-(benzyloxyamino)-pent-4-enoate | 1373273-92-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl 2-(benzyloxyamino)-pent-4-enoate
• 英文别名: Ethyl 2-(phenylmethoxyamino)pent-4-enoate
• CAS: 1373273-92-7
• 化学式: C₁₄H₁₉NO₃
• 分子量: 249.31
• InChiKey: MYAHYMVSNHHPOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  ethyl 2-((benzyloxy)imino)acetate 、 3-溴丙烯 在 indium 作用下， 以 四氢呋喃 为溶剂， 反应 4.17h， 以89%的产率得到ethyl 2-(benzyloxyamino)-pent-4-enoate
  参考文献：
  名称：

  Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation

  摘要：

  A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Reformatsky reaction on oxime ethers. (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2011.11.012

文献信息

• Indium-mediated allylation and Reformatsky reaction on glyoxylic oximes under ultrasound irradiation
  作者：Raquel G. Soengas、Amalia M. Estévez

  DOI：10.1016/j.ultsonch.2011.11.012

  日期：2012.7

  A novel and more convenient method for the indium-promoted allylation of glyoxylic oximes based on the use of ultrasonic waves is reported. A similar procedure was used to develop the first example reported in the literature of an indium-mediated Reformatsky reaction on oxime ethers. (C) 2011 Elsevier B.V. All rights reserved.