2,4,7-trimethyl-5,6-dihydro-1H-indole-3,5,6-triol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2,4,7-trimethyl-5,6-dihydro-1H-indole-3,5,6-triol
• 化学式: C₁₁H₁₅NO₃
• 分子量: 209.24
• InChiKey: RROVVVPNNUMUFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  72.7
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• METHOD OF PREPARING COATING FILM CONTAINING NITROGEN MONOXIDE ON SURFACE OF MATERIAL USING CATECHOLAMINE
  申请人：POSTECH ACADEMY-INDUSTRY FOUNDATION

  公开号：US20140127277A1

  公开（公告）日：2014-05-08

  A method of coating surfaces of various body-implantable materials with control-releasable nitrogen monoxide using a catecholamine, more particularly, technology of preparing a coating film containing a diazeniumdiolate functional group on a surface of a material to be coated using a catecholamine, is provided. The coating film prepared by the method has advantages in that nitrogen monoxide can be stably supplied under an in vivo environment, and can be suitably used in a living body without causing cytotoxicity. Therefore, among the materials having a coating film formed on a surface thereof, the body-implantable material is especially expected to be widely used for medical and health applications including treatment of ischemic disorders such as arteriosclerosis through controlled release of nitrogen monoxide, regulation of penile erections, antibacterial and antiviral effects, and wound healing.
• US9623156B2
  申请人：——

  公开号：US9623156B2

  公开（公告）日：2017-04-18