3-(4-Ethoxy-2-hydroxy-phenyl)-buttersaeurehydrazid | 24535-08-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(4-Ethoxy-2-hydroxy-phenyl)-buttersaeurehydrazid
• 英文别名: 4-ethoxy-2-hydroxy-β-methyl-hydrocinnamic acid, hydrazide；3-(4-Ethoxy-2-hydroxyphenyl)butanehydrazide
• CAS: 24535-08-8
• 化学式: C₁₂H₁₈N₂O₃
• 分子量: 238.287
• InChiKey: HOLWEDOJJIPTTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  84.6
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  7-乙氧基-4-甲基香豆素 生成 3-(4-Ethoxy-2-hydroxy-phenyl)-buttersaeurehydrazid
  参考文献：
  名称：

  Allen,C.F.H.; Weismann Magder,E., Journal of Heterocyclic Chemistry, 1969, vol. 6, p. 349 - 360

  摘要：

  DOI：

文献信息

• [EN] RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE<br/>[FR] UTILISATION COSMÉTIQUE DES DÉRIVÉS DU RÉSORCINOL
  申请人：OREAL

  公开号：WO2017102802A1

  公开（公告）日：2017-06-22

  The present invention relates to a compound of formula (I) for its depigmenting, lightening and/or bleaching the skin in which R1 and R2 independently denote H, an alkyl radical, a radical S* denoting a monosaccharide sugar radical or a polysaccharide sugar radical, a radical COR6; R3 denotes a C1-C20 alkyl radical; R4 and R5 independently denote H, a saturated C1-C20 or unsaturated C2-C20 or branched C3-C20, or cyclic C3-C8 alkyl radical, which is optionally interrupted and/or optionally substituted; R7 and R8, which may be identical or different, being chosen from H, an unsaturated linear C1-C10 alkyl group, an unsaturated linear C2-C10 alkyl group, a saturated or unsaturated branched C3-C10 alkyl group, and a C3-C8 cycloalkyl group; a (C1-C4)alkyl(hetero)(C6)aryl group optionally containing a nitrogen atom, especially a benzyl group; an acetyl radical, and also the salts thereof, the solvates thereof and the optical and/or geometrical isomers thereof, and the racemic mixtures thereof, alone or as a mixture. The present invention also relates to novel compounds (II), and also to the process for preparing them and to a cosmetic process for depigmenting the skin using such compounds (I) or (II).