5-methoxy-2-methyl-1H-indole-4-carbonitrile

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5-methoxy-2-methyl-1H-indole-4-carbonitrile
• 化学式: C₁₁H₁₀N₂O
• 分子量: 186.21
• InChiKey: WKPIYLULBIQLAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  48.8
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] SUBSTITUTED INDOL-5-OL DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS<br/>[FR] DÉRIVÉS INDOL-5-OLE SUBSTITUÉS ET LEURS APPLICATIONS THÉRAPEUTIQUES
  申请人：NANT HOLDINGS IP LLC

  公开号：WO2014071378A9

  公开（公告）日：2015-02-05
• PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THEIR THERAPEUTICAL APPLICATIONS
  申请人：NantBioScience, Inc.

  公开号：EP3261638B1

  公开（公告）日：2019-05-08
• SUBSTITUTED INDOL-5-OL DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
  申请人：NANTBIOSCIENCE, INC

  公开号：US20160016945A1

  公开（公告）日：2016-01-21

  The present invention relates generally to the use of compounds to treat a variety of disorders, diseases and pathologic conditions and more specifically to the use of substituted indol-5-ol derivatives to modulate protein kinases and for treating protein kinase-mediated diseases.
• SUBSTITUTED INDOL-5-OL DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS
  申请人：NantBioScience, Inc.

  公开号：US20170088544A1

  公开（公告）日：2017-03-30

  The present invention relates generally to the use of compounds to treat a variety of disorders, diseases and pathologic conditions and more specifically to the use of substituted indol-5-ol derivatives to modulate protein kinases and for treating protein kinase-mediated diseases.
• US9550760B2
  申请人：——

  公开号：US9550760B2

  公开（公告）日：2017-01-24