Tert-butyl 2-[4-[(1-benzylpiperidin-4-yl)amino]phenyl]-6-cyanoindole-1-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: Tert-butyl 2-[4-[(1-benzylpiperidin-4-yl)amino]phenyl]-6-cyanoindole-1-carboxylate
• 英文别名: tert-butyl 2-[4-[(1-benzylpiperidin-4-yl)amino]phenyl]-6-cyanoindole-1-carboxylate
• 化学式: C₃₂H₃₄N₄O₂
• 分子量: 506.6
• InChiKey: BACGAJUZIPPZCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  38
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  70.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• INDOLE COMPOUNDS AND THEIR USE AS ANTIMICROBIALS
  申请人：Memorial Sloan-Kettering Cancer Center

  公开号：US20150291565A1

  公开（公告）日：2015-10-15

  Indole compounds of formula I, as well as compositions including the compounds and methods for their use, are disclosed that are useful for treating bacterial and/or fungal infections. Indole compounds of formula I, compositions and methods are disclosed that also are useful for killing or inhibiting the growth of bacteria and/or fungus:
• [EN] INDOLE COMPOUNDS AND THEIR USE AS ANTIMICROBIALS<br/>[FR] COMPOSÉS INDOLES ET LEUR UTILISATION EN TANT QU'ANTIMICROBIENS
  申请人：SLOAN KETTERING INST CANCER

  公开号：WO2014078294A1

  公开（公告）日：2014-05-22

  Indole compounds of formula I, as well as compositions including the compounds and methods for their use, are disclosed that are useful for treating bacterial and/or fungal infections. Indole compounds of formula I, compositions and methods are disclosed that also are useful for killing or inhibiting the growth of bacteria and/or fungus: (I).