[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-5-(6-benzamidopurin-9-yl)-2-[[2-cyanoethoxy-[(2R,4S,5R)-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-2-(hydroxymethyl)oxolan-3-yl]oxyphosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,3-dihydropyrrol-1-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-5-[2-(2-methylpropylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl] 4-oxopentanoate

分子结构分类

有机化合物 - 核苷、核苷酸和类似物 - 核苷和核苷酸类似物

中文名称

——

中文别名

——

英文名称

[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-5-(6-benzamidopurin-9-yl)-2-[[2-cyanoethoxy-[(2R,4S,5R)-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-2-(hydroxymethyl)oxolan-3-yl]oxyphosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,3-dihydropyrrol-1-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-5-[2-(2-methylpropylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl] 4-oxopentanoate

英文别名

——

[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-2-[[[(2R,4S,5R)-5-(6-benzamidopurin-9-yl)-2-[[2-cyanoethoxy-[(2R,4S,5R)-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-2-(hydroxymethyl)oxolan-3-yl]oxyphosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,3-dihydropyrrol-1-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]-5-[2-(2-methylpropylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-(2-cyanoethoxy)phosphoryl]oxymethyl]-5-(2,6-dihydro-1,3-oxazin-3-yl)-4-[2-[hydroxy(dimethyl)silyl]-2-methylpropyl]oxolan-3-yl] 4-oxopentanoate化学式

CAS

——

化学式

C₁₀₅H₁₆₇N₁₇O₃₄P₄Si₅

mdl

——

分子量

2475.9

InChiKey

FACWVNKBDVVFNW-NVEUVCBCSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

16.03
重原子数：

165
可旋转键数：

63
环数：

13.0
sp3杂化的碳原子比例：

0.72
拓扑面积：

657
氢给体数：

9
氢受体数：

45

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