1,2,2,3,4,5-Hexachloro-4,6,6-trimethyl-1,3,5-triazinane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪烷类
• 英文名称: 1,2,2,3,4,5-Hexachloro-4,6,6-trimethyl-1,3,5-triazinane
• 英文别名: 1,2,2,3,4,5-hexachloro-4,6,6-trimethyl-1,3,5-triazinane
• 化学式: C₆H₉Cl₆N₃
• 分子量: 335.9
• InChiKey: IEHLGFQDRAWPFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Chemical bleaching of dyes using radical photoinitiators
  申请人：GE Healthcare Bio-Sciences Corp.

  公开号：US10677802B2

  公开（公告）日：2020-06-09

  Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated.

  本发明提供的方法包括使用光激活化学漂白法检测生物样本中的多个靶标。这些方法包括以下步骤：将至少一个探针与生物样本中的一个或多个靶标（包括多个靶标）结合，并检测探针发出的信号。该方法还包括以下步骤：将包含结合探针的样品与光引发剂接触，并照射样品，从而启动光激活化学漂白过程，使探针基本失活。该方法还包括以下步骤：将至少一个探针与样品中的一个或多个靶标结合，并检测探针发出的信号。结合、检测和漂白过程可以反复进行。
• CHEMICAL BLEACHING OF DYES USING RADICAL PHOTOINITIATORS
  申请人：CLARIENT DIAGNOSTIC SERVICES INC.

  公开号：US20150285813A1

  公开（公告）日：2015-10-08

  Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated.
• [EN] CHEMICAL BLEACHING OF DYES USING RADICAL PHOTOINITIATORS<br/>[FR] BLANCHIMENT CHIMIQUE DE COLORANTS AU MOYEN DE PHOTO-INITIATEURS DE RADICAUX
  申请人：CLARIENT DIAGNOSTIC SERVICES INC

  公开号：WO2014099222A1

  公开（公告）日：2014-06-26

  Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of binding at least one probe to one or more target present in a biological sample including multiple targets, and detecting a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a photoinitiator and irradiating the sample, thereby initiating a photoactivated chemical bleaching process that substantially inactivates the probe. The method further includes the steps of binding at least one probe to one or more target present in the sample, and detecting a signal from the probe. The process of binding, detecting and bleaching may be iteratively repeated.