sodium;2,5-dioxooxolane-3-sulfonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: sodium;2,5-dioxooxolane-3-sulfonate
• 化学式: C4H3NaO6S
• 分子量: 202.12
• InChiKey: QVZVAUZTNCXLPV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.62
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  109
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  磺基琥珀酸 、 sodium hydroxide 、 乙酸酐 在 乙酸乙酯 、 white crystalline product 作用下， 以 乙酸乙酯 为溶剂， 反应 6.0h， 生成 sodium;2,5-dioxooxolane-3-sulfonate
  参考文献：
  名称：

  Method for the preparation of sulfo-N-hydroxy succinimade salts

  摘要：

  一种磺化琥珀酸盐被环化，然后通过与羟胺反应（羟胺可以添加或原位形成）转化为新的磺化羟胺酸，并将新的羟胺酸环化为磺化-N-羟基琥珀酰亚胺盐。这种合成过程简单、直接，比目前的琥珀酰亚胺合成过程更快。在这个过程中，形成了新的磺化羟胺酸中间体。

  公开号：

  US05942628A1

文献信息

• Preparation of sulfo-N-hydroxysuccinimide salts
  申请人：Pierce Chemical Company

  公开号：US05892057A1

  公开（公告）日：1999-04-06

  The salt of a sulfonated succinic acid is cyclized, then converted to novel sulfonated hydroxamic acids by reaction with hydroxylamine (which is added or formed in situ), and the novel hydroxamic acid is then cyclized to the sulfo-N-hydroxysuccinimide salt. This synthetic procedure is simple, direct, and more rapid than present procedures for synthesis of the succinimide. Novel sulfo-hydroxamic acid intermediates are formed during this procedure.

  磺化琥珀酸的盐被环化，然后通过与羟胺反应（添加或原位形成）转化为新的磺化羟肟酸，然后将新的羟肟酸环化为磺酰-N-羟基琥珀酰亚胺盐。这种合成方法简单、直接，比目前合成琥珀酰亚胺的方法更快。在此过程中形成了新的磺化羟肟酸中间体。
• Method for the preparation of sulfo-N-hydroxy succinimade salts
  申请人：Pierce Chemical Company

  公开号：US05942628A1

  公开（公告）日：1999-08-24

  The salt of a sulfonated succinic acid is cyclized, then converted to novel sulfonated hydroxamic acids by reaction with hydroxylamine (which is added or formed in situ), and the novel hydroxamic acid is then cyclized to the sulfo-N-hydroxysuccinimide salt. This synthetic procedure is simple, direct, and more rapid than present procedures for synthesis of the succinimide. Novel sulfo-hydroxamic acid intermediates are formed during this procedure.

  一种磺化琥珀酸盐被环化，然后通过与羟胺反应（羟胺可以添加或原位形成）转化为新的磺化羟胺酸，并将新的羟胺酸环化为磺化-N-羟基琥珀酰亚胺盐。这种合成过程简单、直接，比目前的琥珀酰亚胺合成过程更快。在这个过程中，形成了新的磺化羟胺酸中间体。
• Preparation of sulfo-N-hydroxy succinimide salts
  申请人：Pierce Chemical Company

  公开号：US06407263B1

  公开（公告）日：2002-06-18

  The salt of a sulfonated succinic acid is cyclized, then converted to novel sulfonated hydroxamic acids by reaction with hydroxylamine (which is added or formed in situ), and the novel hydroxamic acid is then cyclized to the sulfo-N-hydroxysuccinimide salt. This synthetic procedure is simple, direct, and more rapid than present procedures for synthesis of the succinimide. Novel sulfo-hydroxamic acid intermediates are formed during this procedure.

  磺化琥珀酸盐被环化，然后通过与羟胺反应（羟胺可以添加或原位形成）转化为新型的磺化羟肟酸，然后将新型羟肟酸环化为磺酰-N-羟基琥珀酰亚胺盐。这种合成方法简单、直接，比目前合成琥珀酰亚胺的方法更快。在这个过程中形成了新型的磺化羟肟酸中间体。