1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]ethyl dihydrogen phosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 核苷和核苷酸类似物
• 英文名称: 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(1-methyl-2,4-dioxopyrimidin-5-yl)oxolan-2-yl]ethyl dihydrogen phosphate
• 化学式: C₁₁H₁₇N₂O₉P
• 分子量: 352.23
• InChiKey: OUIIJQUKTGFRMP-YGCUGPIZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  166
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• MODIFIED POLYNUCLEOTIDES ENCODING CITED4
  申请人：MODERNA THERAPEUTICS, INC.

  公开号：US20140186432A1

  公开（公告）日：2014-07-03

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF COSMETIC PROTEINS AND PEPTIDES
  申请人：Moderna Therapeutics, Inc.

  公开号：US20150166616A1

  公开（公告）日：2015-06-18

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of cosmetic polynucleotides, cosmetic primary transcripts and cosmetic mmRNA molecules.