3-(Decyloxy)benzyl methanesulfonate Triethylamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-(Decyloxy)benzyl methanesulfonate Triethylamine
• 英文别名: (3-decoxyphenyl)methyl methanesulfonate;N,N-diethylethanamine
• 化学式: C24H45NO4S
• 分子量: 443.7
• InChiKey: MWXQYAZWIRNKLO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.03
• 重原子数：
  30
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  64.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  3-(Decyloxy)benzyl methanesulfonate Triethylamine 、 [3-(decyloxy)phenyl]methanamine 、 甲基磺酰氯 、 水 在 ice 、 乙酸乙酯 、 水 、 碳酸氢钠 、 盐酸 、 Brine 、 Sodium sulfate-III 、 silica gel 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 以to give 23.53 g of 3-(decyloxy)benzyl methanesulfonate as an amber oil that的产率得到3-(decyloxy)benzyl methanesulfonate
  参考文献：
  名称：

  AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY

  摘要：

  本文描述了对炎症、真菌、单细胞寄生微生物和癌症具有活性的胺化合物。这些化合物包含一个单环、双环或三环芳香环，其中含有一个、两个或三个环氮原子。

  公开号：

  US20150361077A1

文献信息

• Aminoquinazoline compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
  申请人：Wellstat Therapeutics Corporation

  公开号：US10934284B2

  公开（公告）日：2021-03-02

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

  本文描述了具有抗炎、抗真菌、抗单细胞寄生微生物和抗癌活性的胺化合物。这些化合物含有单环、双环或三环芳香环，环上有一个、两个或三个氮原子。
• AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：EP2950649B1

  公开（公告）日：2020-03-04
• AMINOQUINOLINE COMPOUNDS HAVING ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：US20180298000A1

  公开（公告）日：2018-10-18

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
• AMINOQUINAZOLINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：US20190194193A1

  公开（公告）日：2019-06-27

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.
• IMIDAZOQUINOLYL COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC, AND ANTICANCER ACTIVITY
  申请人：Wellstat Therapeutics Corporation

  公开号：US20210163476A1

  公开（公告）日：2021-06-03

  Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.