[2-Hydroxy-4-[4-(3-hydroxy-4-methoxyphenyl)-2,3-dimethylbutyl]phenyl] dihydrogen phosphate

• 分子结构分类: 有机化合物 - 木脂素、新木脂素和相关化合物 - 二苄基丁烷木脂素
• 英文名称: [2-Hydroxy-4-[4-(3-hydroxy-4-methoxyphenyl)-2,3-dimethylbutyl]phenyl] dihydrogen phosphate
• 英文别名: [2-hydroxy-4-[4-(3-hydroxy-4-methoxyphenyl)-2,3-dimethylbutyl]phenyl] dihydrogen phosphate
• 化学式: C₁₉H₂₅O₇P
• 分子量: 396.4
• InChiKey: NYHKZGXKDIASSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• [EN] CANCER THERAPY<br/>[FR] CANCÉROTHÉRAPIE
  申请人：TRIACT THERAPEUTICS INC

  公开号：WO2014134202A1

  公开（公告）日：2014-09-04

  The present application relates to compositions and methods for treating a proliferative disorder by administering to a subject a pharmaceutical composition of a dual kinase inhibitor metabolite. Catecholic butane metabolites can serve as dual kinase inhibitors for purposes of methods described herein. Proliferative diseases are a serious threat to modem society. Cancerous growths, including malignant cancerous growth, pose serious challenges for modem medicine due to their unique characteristics.