9-(hydroxymethyl)-3-methyl-5,7,9a,9b-tetrahydro-4aH-pyrano[2,3-a]pyrrolizin-2-one

• 分子结构分类: 有机化合物 - 生物碱及其衍生物
• 英文名称: 9-(hydroxymethyl)-3-methyl-5,7,9a,9b-tetrahydro-4aH-pyrano[2,3-a]pyrrolizin-2-one
• 化学式: C₁₂H₁₅NO₃
• 分子量: 221.25
• InChiKey: LIMCPFYSYRPKCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] ARTHROPOD CONTROLLING COMPOSITION<br/>[FR] COMPOSITION DE LUTTE CONTRE LES ARTHROPODES
  申请人：FIRMENICH & CIE

  公开号：WO2020239980A1

  公开（公告）日：2020-12-03

  The present invention relates to an arthropod controlling composition comprising a compound according to formula (I), methods and uses to control arthropods as well as arthropod controlling articles comprising the same.

  本发明涉及一种包括根据式(I)的化合物的节肢动物控制组合物，以及用于控制节肢动物的方法和用途，以及包含相同化合物的节肢动物控制物品。
• METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS
  申请人：The Regents of the University of California

  公开号：EP3409115A2

  公开（公告）日：2018-12-05

  Provided herein are screening methods for identifying compounds for use as an arthropod repellent based on the masking or inhibition of the detection of the skin odor by a cpA neuron. Provided herein are also screening methods for identifying compounds for use as an arthropod attractant based on activation of the cpA neuron. Further provided are one or more compounds identified using the screening methods described herein, and compositions containing such compounds.

  本文提供了根据掩蔽或抑制 cpA 神经元对皮肤气味的检测来确定用作节肢动物驱避剂的化合物的筛选方法。本文还提供了根据 cpA 神经元的激活来鉴定用作节肢动物吸引剂的化合物的筛选方法。此外，还提供了使用本文所述筛选方法鉴定出的一种或多种化合物，以及含有此类化合物的组合物。
• Methods for identifying arthropod repellents and attractants, and compounds and compositions identified by such methods
  申请人：The Regents of the University of California

  公开号：US10768168B2

  公开（公告）日：2020-09-08

  Provided herein are screening methods for identifying compounds for use as an arthropod repellent based on the masking or inhibition of the detection of the skin odor by a cpA neuron. Provided herein are also screening methods for identifying compounds for use as an arthropod attractant based on activation of the cpA neuron. Further provided are one or more compounds identified using the screening methods described herein, and compositions containing such compounds.

  本文提供了根据掩蔽或抑制 cpA 神经元对皮肤气味的检测来确定用作节肢动物驱避剂的化合物的筛选方法。本文还提供了根据 cpA 神经元的激活来鉴定用作节肢动物吸引剂的化合物的筛选方法。此外，还提供了使用本文所述筛选方法鉴定出的一种或多种化合物，以及含有此类化合物的组合物。
• METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS
  申请人：The Regents of the University of California

  公开号：EP2972299A2

  公开（公告）日：2016-01-20
• ARTHROPOD CONTROLLING COMPOSITION
  申请人：Firmenich SA

  公开号：EP3930461A1

  公开（公告）日：2022-01-05