butanoyl-N(Me)Dha-N(Me)Leu-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-NHMe

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: butanoyl-N(Me)Dha-N(Me)Leu-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-NHMe
• 英文别名: (2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[2-[butanoyl(methyl)amino]prop-2-enoyl-methylamino]-4-methylpentanoyl]amino]-3-methylbutanoyl]-methylamino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]-methylamino]-N,4-dimethylpentanamide
• 化学式: C₄₁H₇₄N₈O₈
• 分子量: 807.1
• InChiKey: GFJUDZZTSXQHEU-JCHPCLRWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  57
• 可旋转键数：
  23
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  198
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• [EN] NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION<br/>[FR] NOUVEAUX DÉRIVÉS DE CICLOSPORINE DESTINÉS AU TRAITEMENT ET À LA PRÉVENTION D'UNE INFECTION VIRALE
  申请人：S & T GLOBAL INC

  公开号：WO2012075494A1

  公开（公告）日：2012-06-07

  The present invention relates to a compound of the Formula (I): or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing a viral infection using the same.
• [EN] NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF<br/>[FR] NOUVEAUX DÉRIVÉS DE CYCLOSPORINE ET LEURS UTILISATIONS
  申请人：SU ZHUANG

  公开号：WO2014145686A2

  公开（公告）日：2014-09-18

  The present invention relates to a compound of the Formula (I)): or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing viral infections, inflammation, dry eye, central nervous disorders, cardiovascular diseases, cancer, obesity, diabetes, muscular dystrophy, and hair loss.