(E,5Z)-5-(hydroxymethylidene)-4-propan-2-yloct-6-enoic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: (E,5Z)-5-(hydroxymethylidene)-4-propan-2-yloct-6-enoic acid
• 化学式: C₁₂H₂₀O₃
• 分子量: 212.28
• InChiKey: RXIFLOBTEAVVRR-OOFLMXFCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• US20140275236A1
  申请人：——

  公开号：US20140275236A1

  公开（公告）日：2014-09-18
• Novel anti-neurodegenerative natural compounds isolated from Alpiniae Oxyphyllae Fructus and their total synthesis
  申请人：University of Macau

  公开号：US20160376216A1

  公开（公告）日：2016-12-29

  This invention is directed to novel compounds isolated or derived from Alpiniae oxyphyllae fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases such as Parkinson's disease.
• Methods of treating Parkinson's disease
  申请人：University of Macau

  公开号：US20180065912A1

  公开（公告）日：2018-03-08

  This invention is directed to novel compounds isolated or derived from Alpiniae oxyphyllae fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases such as Parkinson's disease.
• US9475749B2
  申请人：——

  公开号：US9475749B2

  公开（公告）日：2016-10-25
• [EN] NOVEL ANTI-NEURODEGENERATIVE NATURAL COMPOUNDS ISOLATED FROM ALPINIAE OXYPHYLLAE FRUCTUS AND THEIR TOTAL SYNTHESIS<br/>[FR] NOUVEAUX COMPOSÉS NATURELS ANTI-NEURODÉGÉNÉRATIFS ISOLÉS À PARTIR DE ALPINIAE OXYPHYLLAE FRUCTUS ET LEUR SYNTHÈSE TOTALE
  申请人：UNIV MACAU

  公开号：WO2014141169A2

  公开（公告）日：2014-09-18

  This invention is directed to novel compounds isolated or derived from Alpiniae oxyphyllae fructus, chemically synthesized novel compounds, methods of preparing the novel compounds and uses thereof as neuroprotectants or drugs for treating neurodegenerative diseases such as Parkinson's disease.