5-羟基月桂酸 | 7779-95-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 5-羟基月桂酸
• 英文名称: 5-hydroxydodecanoic acid
• 英文别名: 5-Hydroxy-dodecansaeure
• CAS: 7779-95-5
• 化学式: C₁₂H₂₄O₃
• 分子量: 216.321
• InChiKey: LXNOENXQFNYMGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 危险性防范说明：
  P261,P264,P270,P271,P280,P302+P352,P304+P340,P305+P351+P338,P312,P330,P362,P403+P233,P501
• 危险性描述：
  H302,H312,H332

反应信息

• 作为产物：
  描述：

  5-氧代十二烷酸 在 aluminum isopropoxide 作用下， 生成 5-羟基月桂酸
  参考文献：
  名称：

  Lardelli,G. et al., Recueil des Travaux Chimiques des Pays-Bas, 1967, vol. 86, p. 481 - 503

  摘要：

  DOI：

文献信息

• [EN] PHOSPHORIC ACID ESTERS AND THEIR USE AS WETTING AND DISPERSING AGENT<br/>[FR] ESTERS D'ACIDE PHOSPHORIQUE ET LEUR UTILISATION COMME AGENT MOUILLANT ET DISPERSANT
  申请人：EFKA ADDITIVES B V

  公开号：WO2005085261A1

  公开（公告）日：2005-09-15

  The invention relates to a phosphoric acid ester and salts thereof of the general formula (I), wherein A is a monohydroxyl residue derived from C1-C20-alkyl-(AO)x-OH or Acyl-(AO)x-OH; or C1-C20-alkyl -(AO)x-(HA)y-OH or Acyl-(AO)x-(HA)y-OH; or C1-C20-alkyl -(AO)x-(AA-AO)y-OH or Acyl-(AO)x-(AA-AO)y-OH; or MO -(HA)y-OH or MO-(AA-AO)y-OH; wherein Acyl is an aromatic carboxylic acid residue or a saturated or unsaturated fatty acid residue; AO is a polyC2-C4alkyleneglycol residue, HA is a hydroxycarboxylic acid or a lactone thereof, AA is a dicarboxylic acid, MO is a monoalcohol, x is 1 to 250, y is 1 to 250, B is a mono-, di-, or tri- or polyhydroxy di-, tri or multi-carboxylic acid residue which is linked via the hydroxy group to the phosphoric acid and via one of the carboxylic acid groups to the monohydroxyl residue [A], the remaining carboxyl acid group(s) is/are free or is/are esterified with a further monohydroxyl residue [A], resulting in branched esters; n is 1-2; m is 1-4. The phosphoric acid esters are used as wetting agent or dispersants.

  该发明涉及一种磷酸酯及其盐，其通式为(I)，其中A是由C1-C20-烷基-(AO)x-OH或酰基-(AO)x-OH衍生的单羟基残基；或C1-C20-烷基-(AO)x-(HA)y-OH或酰基-(AO)x-(HA)y-OH；或C1-C20-烷基-(AO)x-(AA-AO)y-OH或酰基-(AO)x-(AA-AO)y-OH；或MO-(HA)y-OH或MO-(AA-AO)y-OH；其中酰基是芳香族羧酸残基或饱和或不饱和脂肪酸残基；AO是聚C2-C4烷基二醇残基，HA是羟基羧酸或其内酯，AA是二羧酸，MO是单醇，x为1至250，y为1至250，B是通过羟基与磷酸酯相连的单羟基残基[A]，其余羧基是自由的或与另一单羟基残基[A]酯化，形成支链酯；n为1-2；m为1-4。该磷酸酯用作润湿剂或分散剂。
• NOVEL ALKANETHIOIC ACID DERIVATIVE AND PERFUME COMPOSITION CONTAINING THE SAME
  申请人：T. HASEGAWA CO., LTD.

  公开号：US20200290958A1

  公开（公告）日：2020-09-17

  An alkanethioic acid derivative capable of imparting a characteristic aroma or flavor to fragrances and cosmetics, and foods and beverages; and a perfume composition comprising the alkanethioic acid derivative as an active ingredient. S-alkyl 5-[(1-alkoxy)ethoxy]alkanethioate represented by formula (1), and a perfume composition comprising the S-alkyl 5-[(1-alkoxy)ethoxy]alkanethioate represented by formula (1) as an active ingredient. In the formula (1), R 1 represents an alkyl group having 1 to 9 carbon atoms, R2 represents an alkyl group having 2 to 4 carbon atoms, and R3 represents a methyl group or an ethyl group.

  一种烷硫酸衍生物，能够赋予香水、化妆品、食品和饮料特有的香气或风味；以及一种香水组合物，其包括所述烷硫酸衍生物作为活性成分。公式（1）表示的S-烷基5-[(1-烷氧基)乙氧基]烷硫酸酯，以及包括公式（1）表示的S-烷基5-[(1-烷氧基)乙氧基]烷硫酸酯作为活性成分的香水组合物。在公式（1）中，R1代表具有1至9个碳原子的烷基基团，R2代表具有2至4个碳原子的烷基基团，R3代表甲基基团或乙基基团。
• IONIC LIQUID SYSTEMS
  申请人：The Procter & Gamble Company

  公开号：US20160177222A1

  公开（公告）日：2016-06-23

  The present invention relates to an ionic liquid system for enhanced delivery and/or deposition of a perfume raw material onto a substrate, particularly fabric, hard surfaces, soft surfaces, skin, or hair. The invention also relates to consumer products comprising the new ionic liquid systems, and processes for making and methods of using such ionic liquid systems and consumer products.

  本发明涉及一种离子液体系统，用于增强香水原料在基底上的传递和/或沉积，特别是织物、硬表面、软表面、皮肤或头发。该发明还涉及包含新离子液体系统的消费产品，以及制造和使用这种离子液体系统和消费产品的方法。
• Cascade Biotransformations via Enantioselective Reduction, Oxidation, and Hydrolysis: Preparation of (<i>R</i>)-δ-Lactones from 2-Alkylidenecyclopentanones
  作者：Ji Liu、Zhi Li

  DOI：10.1021/cs400101v

  日期：2013.5.3

  cascade biotransformation involving enantioselective reduction of a C═C double bond, Baeyer–Villiger oxidation, and lactone hydrolysis was developed as a green and sustainable tool for synthesizing enantiopure δ-lactones. One-pot cascade biotransformations were achieved with Acinetobacter sp. RS1 containing a novel enantioselective reductase and an enantioselective lactone hydrolase and Escherichia coli

  作为涉及绿色和可持续的合成对映纯δ-内酯的工具，首次涉及级联生物转化涉及C═C双键的对映选择性还原，Baeyer-Villiger氧化和内酯水解。不动杆菌属一锅级联生物转化。RS1含有新颖的对映选择性还原酶和对映体选择性内酯水解酶和大肠杆菌共表达的环己酮单加氧酶和葡糖脱氢酶，转换容易获得的2- alkylidenecyclopentanones 1 - 2成相应的有价值的香精香料（[R）-δ-内酯5 - 6在高ee中。一锅法合成优于报道的两步法制备。该概念对于开发其他包含C═C双键的底物的氧化还原级联反应很有用。
• Baeyer–Villiger Oxidation of Cyclic Ketones Using Aqueous Hydrogen Peroxide Catalyzed by Potassium Salts of Tungstophosphoric Acid
  作者：Qingguo Ma、Wanzhen Xing、Junhui Xu、Xinhua Peng

  DOI：10.1246/cl.140159

  日期：2014.6.5

  The salts of 12-tungstophosphoric acid catalysts are prepared with varying potassium content. The resulting catalysts are active for the Baeyer–Villiger oxidation of cyclic ketones with 30 wt % H2O...

  12-钨磷酸催化剂的盐是用不同的钾含量制备的。所得催化剂对环酮与 30 wt % H2O 的 Baeyer-Villiger 氧化具有活性...