N,N-bis[[1-(pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl]methyl](prop-2-yn-1)amine | 1402329-64-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: N,N-bis[[1-(pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl]methyl](prop-2-yn-1)amine
• 英文别名: N,N-Bis((1-(pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl)methyl)prop-2-yn-1-amine；N,N-bis[[1-(pyren-1-ylmethyl)triazol-4-yl]methyl]prop-2-yn-1-amine
• CAS: 1402329-64-9
• 化学式: C₄₃H₃₁N₇
• 分子量: 645.766
• InChiKey: MOYIKWHGYXWRQM-UHFFFAOYSA-N

物化性质

• 密度：
  1.32±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.4
• 重原子数：
  50
• 可旋转键数：
  9
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  64.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  三炔丙基胺 、 1-(叠氮基甲基)芘 在 2,6-二甲基吡啶 、 tetrakis(actonitrile)copper(I) hexafluorophosphate 作用下， 以 乙腈 为溶剂， 反应 72.0h， 以62%的产率得到N,N-tris[[1-(pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl]methyl]-amine
  参考文献：
  名称：

  A Ratiometric Fluorescent On–Off Zn²⁺ Chemosensor Based on a Tripropargylamine Pyrene Azide Click Adduct

  摘要：

  A new, easy-to-prepare and highly selective pyrene-linked tris-triazole amine fluorescent chemosensor has been designed from tripropargylamine and pyrene azide using Cu(I)-catalyzed click chemistry. The fluorescence on-off sensor 1 is highly selective for Zn2+ displaying a ratiometric change in emission. The relative intensity ratio of monomer to excimer fluorescence (M-376/E-465) of the sensor increases 80-fold upon the addition of 10 equiv of Zn2+ ions (with a detection limit of 0.2 mu M).

  DOI：

  10.1021/jo3014319

文献信息

• A Ratiometric Fluorescent On–Off Zn²⁺ Chemosensor Based on a Tripropargylamine Pyrene Azide Click Adduct
  作者：Sachin A. Ingale、Frank Seela

  DOI：10.1021/jo3014319

  日期：2012.10.19

  A new, easy-to-prepare and highly selective pyrene-linked tris-triazole amine fluorescent chemosensor has been designed from tripropargylamine and pyrene azide using Cu(I)-catalyzed click chemistry. The fluorescence on-off sensor 1 is highly selective for Zn2+ displaying a ratiometric change in emission. The relative intensity ratio of monomer to excimer fluorescence (M-376/E-465) of the sensor increases 80-fold upon the addition of 10 equiv of Zn2+ ions (with a detection limit of 0.2 mu M).