[1-cyano-7-[[2-[2-[3-[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxy]-2,2-bis[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxymethyl]propoxy]ethoxy]acetyl]amino]heptan-2-yl] N-[4-(diethylcarbamoyl)phenyl]-N-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamate

分子结构分类

有机化合物 - 生物碱及其衍生物 - 喜树碱

中文名称

——

中文别名

——

英文名称

[1-cyano-7-[[2-[2-[3-[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxy]-2,2-bis[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxymethyl]propoxy]ethoxy]acetyl]amino]heptan-2-yl] N-[4-(diethylcarbamoyl)phenyl]-N-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamate

英文别名

——

[1-cyano-7-[[2-[2-[3-[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxy]-2,2-bis[2-[2-[[7-cyano-6-[[4-(diethylcarbamoyl)phenyl]-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamoyl]oxyheptyl]amino]-2-oxoethoxy]ethoxymethyl]propoxy]ethoxy]acetyl]amino]heptan-2-yl] N-[4-(diethylcarbamoyl)phenyl]-N-[[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl]oxymethyl]carbamate化学式

CAS

——

化学式

C₁₉₃H₂₂₈N₂₄O₄₄

mdl

——

分子量

3588.0

InChiKey

WFNAOTLSIZMACE-QLPBUGOUSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

14.4
重原子数：

261
可旋转键数：

100
环数：

24.0
sp3杂化的碳原子比例：

0.48
拓扑面积：

841
氢给体数：

8
氢受体数：

52

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