benzaldehyde dipropargyl acetal | 2188-14-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzaldehyde dipropargyl acetal
• 英文别名: Bis(prop-2-ynoxy)methylbenzene
• CAS: 2188-14-9
• 化学式: C₁₃H₁₂O₂
• 分子量: 200.237
• InChiKey: HLBBLKBSHPAAGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯甲醛 、 2-丙炔-1-醇 在 对甲苯磺酸 作用下， 以 苯 为溶剂， 以89%的产率得到benzaldehyde dipropargyl acetal
  参考文献：
  名称：

  Voronkov, M. G.; Dubinskaya, E. I.; Tsyrendorzhieva, I. P., Journal of applied chemistry of the USSR, 1992, vol. 65, # 12.2, p. 2310 - 2314

  摘要：

  DOI：

文献信息

• Woronkow M. G., Dubinskaja E. I., Chyrendorzhiewa I. P., Legow G. N., Sta+, Zh. prikl. khimii, 65 (1992) N 12, S 2775-2779
  作者：Woronkow M. G., Dubinskaja E. I., Chyrendorzhiewa I. P., Legow G. N., Sta+

  DOI：——

  日期：——
• KALAJDZHYAN, A. E.;AKOPYAN, S. G.;KURGINYAN, K. A., ARM. XIM. ZH., 1986, 39, N 4, 237-242
  作者：KALAJDZHYAN, A. E.、AKOPYAN, S. G.、KURGINYAN, K. A.

  DOI：——

  日期：——
• SUBSTRATES FOR O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
  申请人：ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

  公开号：EP1546371A1

  公开（公告）日：2005-06-29
• [EN] SUBSTRATES FOR O<6>-ALKYLGUANINE-DNA ALKYLTRANSFERASE<br/>[FR] SUBSTRATS DE O<6>-ALKYLGUANINE-ADN ALKYLTRANSFERASE
  申请人：ECOLE POLYTECH

  公开号：WO2004031405A1

  公开（公告）日：2004-04-15

  The present invention relates to methods of transferring a label from novel substrates to O6-alkylguanine-DNA alkyltransferases (AGT) and O6-alkylguanine-DNA alkyltransferase fusion proteins, and to novel substrates suitable in such methods. Proteins of interest are incorporated into an AGT fusion protein, the AGT fusion protein is contacted with particular AGT substrates carrying a label, and the AGT fusion protein is detected and optionally further manipulated using the label in a system designed for recognising and/or handling the label. The particular AGT substrates used in the method of the invention are O6-substituted guanine derivatives or related nitrogen containing hydroxy-heterocycles and their sulfur analogs wherein the O6-substituent is an activated methyl derivative suitable for transfer from guanine or the corresponding heterocycle to AGT, and further carrying a label or a plurality of same or different labels. The invention relates also to the novel AGT substrates as such, to methods of manufacture of such novel substrates, and to intermediates useful in the synthesis of such novel AGT substrates.
• Voronkov, M. G.; Dubinskaya, E. I.; Tsyrendorzhieva, I. P., Journal of applied chemistry of the USSR, 1992, vol. 65, # 12.2, p. 2310 - 2314
  作者：Voronkov, M. G.、Dubinskaya, E. I.、Tsyrendorzhieva, I. P.、Legov, G. N.、Stankevich, O. S.、et al.

  DOI：——

  日期：——