7-Dimethyamino-heptansaeure | 928-86-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 7-Dimethyamino-heptansaeure
• 英文别名: 7-(Dimethylamino)heptanoic acid
• CAS: 928-86-9
• 化学式: C₉H₁₉NO₂
• 分子量: 173.255
• InChiKey: OKGNNQZGPSVQSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  7-氯庚酸 在 氢碘酸 作用下， 以 水 、 丙酮 为溶剂， 生成 7-Dimethyamino-heptansaeure
  参考文献：
  名称：

  Olomucki,M., Bulletin de la Societe Chimique de France, 1963, p. 2067 - 2074

  摘要：

  DOI：

文献信息

• Somatostatin antagonists and agonists
  申请人：——

  公开号：US20020091090A1

  公开（公告）日：2002-07-11

  Compounds according to the formula A-B-Z-W, wherein A is selected from (C 6 -C 10 )aryl-, or (C 1 -C 9 )heteroaryl-, which groups may be optionally substituted; B is selected from (a) O, NH, NR 10 , —(CH 2 ) k —O—, —(CH 2 ) k —N—, and —(CH 2 ) k —NR 10 —, where R 10 is (C 1 -C 6 )alkyl and where k is 1 to 6 in each case, or 1 where said group (i) through (iv) is optionally substituted by 1 to 4, preferably 1 to 2, groups selected from (C 1 -C 6 )alkyl, halo, and (C 1 -C 6 )alkyl optionally substituted by 1 to 3 halo atoms wherein one of carbon atoms C 1 , C 2 , C 3 and C 4 of said piperidine or piperazine group is optionally replaced by a carbonyl group; Z and W are as herein described; and pharmaceutically acceptable salts, solvates or hydrates thereof; pharmaceutical compositions thereof; and methods useful to facilitate secretion of growth hormone(GH) in mammels.

  根据公式A-B-Z-W，其中 A选自(C6-C10)芳基或(C1-C9)杂环芳基，这些基团可以选择性地被取代； B选自 (a) O、NH、NR10、—(CH2)k—O—、—(CH2)k—N—和—(CH2)k—NR10—，其中R10为(C1-C6)烷基，k在每种情况下为1至6，或 1所述的该组(i)至(iv)可以选择性地被1至4个，优选1至2个，选自(C1-C6)烷基、卤素和(C1-C6)烷基，该烷基可以选择性地被1至3个卤原子取代，其中所述哌啶或哌嗪基团的碳原子C1、C2、C3和C4中的一个可以选择性地被羰基取代； Z和W如本文所述；以及其药学上可接受的盐、溶剂化合物或水合物；其制药组合物；以及用于促进哺乳动物分泌生长激素(GH)的方法。
• Dioxolane analogs for improved inter-cellular delivery
  申请人：Shire BioChem Inc.

  公开号：US20030013660A1

  公开（公告）日：2003-01-16

  Dioxolane analogs of the following formula: 1 wherein R1 and R2 are defined herein, are useful in the treatment of cancer. For example, the compounds can be used to treat patients with cancer in which the cancer cells are deficient in nucleoside or nucleoside base transporters.

  以下式中的二氧杂环戊烷类似物：其中R1和R2在此处定义，可用于治疗癌症。例如，这些化合物可用于治疗癌症患者，这些患者的癌细胞缺乏核苷或核苷碱基转运蛋白。
• METHOD FOR PRODUCTION OF ORGANIC-INORGANIC COMPLEX, ORGANIC-INORGANIC COMPLEX, AND POLYMERIC COMPOSITE MATERIAL
  申请人：Tamura Kenji

  公开号：US20090227715A1

  公开（公告）日：2009-09-10

  Disclosed are: a method for production of an organic-inorganic complex by intercalation of a positively charged organic compound between layers of a non-swellable layered silicate which is believed to be difficult to achieve under convenient conditions; the organic-inorganic complex; and a layered silicate/polymer nanocomposite using the organic-inorganic complex. The method comprises: step (I) wherein a hydrous layered silicate having a hydroxyl group in its crystalline structure is heat-treated at a temperature not higher than 1,200° C. and lower than the phase transition temperature of the silicate to dehydrate the silicate; and step (II) wherein the dehydrated layered silicate is contacted with an aqueous solution of a positively charged organic compound.

  本发明涉及一种通过将正电有机化合物插层到非膨胀层状硅酸盐的层间来制备有机-无机复合物的方法，该方法被认为在方便条件下很难实现；所述有机-无机复合物；以及使用所述有机-无机复合物的层状硅酸盐/聚合物纳米复合材料。该方法包括：步骤（I），其中将具有晶体结构中羟基的水合层状硅酸盐在不高于1,200℃且低于硅酸盐相变温度的温度下进行热处理以脱水硅酸盐；以及步骤（II），其中将脱水的层状硅酸盐与正电有机化合物的水溶液接触。
• Adhesive resin-silicate composite and multi-layer product thereof
  申请人：SHOWA DENKO KABUSHIKI KAISHA

  公开号：EP0995591A1

  公开（公告）日：2000-04-26

  The present invention relates to an adhesive resin composite comprising from 0.1 to 20 parts by weight of a organophilic layered silicate per 100 parts by weight of a functional group-containing modified polyolefin; and multilayer product comprising at least three layers of a polyolefin-type resin layer, the adhesive resin layer composite and a barrier resin layer. The adhesive resin and the multilayer product are useful in various fields including containers and packing materials required to have chemical resistance, gas barrier property and liquid barrier property, such as gasoline tank.

  本发明涉及一种粘合剂树脂复合材料，其中每 100 份含官能团改性聚烯烃中含有 0.1 至 20 份（按重量计）亲有机层状硅酸盐；以及多层产品，其中至少包括三层聚烯烃类树脂层、粘合剂树脂层复合材料和阻隔树脂层。粘合剂树脂和多层产品可用于各种领域，包括要求具有耐化学性、气体阻隔性和液体阻隔性的容器和包装材料，如汽油罐。
• Solov'ev,V.M. et al., Journal of general chemistry of the USSR, 1961, vol. 31, # 8, p. 2405 - 2411
  作者：Solov'ev,V.M. et al.

  DOI：——

  日期：——