o-Ethylbenzylacetat | 100058-58-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: o-Ethylbenzylacetat
• 英文别名: acetic acid-(2-ethyl-benzyl ester)；Essigsaeure-(2-aethyl-benzylester)；(2-Ethylphenyl)methyl acetate
• CAS: 100058-58-0
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: YZYXIUMENILXAA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  o-Ethylbenzylacetat 在 chromium(VI) oxide 、 溶剂黄146 作用下， 生成 2-acetylbenzyl acetate
  参考文献：
  名称：

  Mitsui et al., Journal of the Scientific Research Institute, Tokyo, 1950, vol. 50, p. 65,71

  摘要：

  DOI：
• 作为产物：
  描述：

  邻乙基苯甲醇 、 溶剂黄146 在 potassium acetate 作用下， 生成 o-Ethylbenzylacetat
  参考文献：
  名称：

  Mitsui et al., Journal of the Scientific Research Institute, Tokyo, 1959, vol. 50, p. 65,70

  摘要：

  DOI：

文献信息

• SKIN SENSITIZATION MEASURING METHOD AND SKIN SENSITIZATION MEASURING REAGENT
  申请人：FUJIFILM Corporation

  公开号：EP3845887A1

  公开（公告）日：2021-07-07

  An object of the present invention is to provide a method for determining skin allergenicity of a mixture containing two or more test substances, and a reagent for determining the skin allergenicity. The present invention provides a method for determining skin allergenicity, the method including causing a reaction between an organic compound that has at least one thiol group or amino group and emits fluorescence, and a mixture containing two or more test substances, and determining an amount of the organic compound after the reaction or an amount of a product of the reaction by an optical measurement using a fluorescence detector; and a reagent for determining skin allergenicity, the reagent including, as a measurement basis, an organic compound that has at least one thiol group or amino group and emits fluorescence, and being used for determining skin allergenicity of a mixture containing two or more test substances by an optical measurement using a fluorescence detector.

  本发明的目的是提供一种测定含有两种或两种以上测试物质的混合物的皮肤过敏性的方法，以及一种测定皮肤过敏性的试剂。本发明提供了一种确定皮肤过敏性的方法，该方法包括使至少有一个硫醇基团或氨基并发射荧光的有机化合物与含有两种或两种以上测试物质的混合物发生反应，并通过使用荧光检测器进行光学测量来确定反应后有机化合物的量或反应产物的量；和一种用于确定皮肤过敏性的试剂，该试剂包括作为测量基础的有机化合物，该有机化合物具有至少一个硫醇基团或氨基并发射荧光，通过使用荧光检测器进行光学测量，用于确定含有两种或两种以上测试物质的混合物的皮肤过敏性。
• CHIRAL DESIGN
  申请人：WAVE LIFE SCIENCES LTD.

  公开号：US20170037399A1

  公开（公告）日：2017-02-09

  The present invention relates to chirally controlled oligonucleotides of select designs, chirally controlled oligonucleotide compositions, and methods of making and using the same. In some embodiments, a provided chirally controlled oligonucleotide composition provides different cleavage patterns of a nucleic acid polymer than a reference oligonucleotide composition. In some embodiments, a provided chirally controlled oligonucleotide composition provides single site cleavage within a complementary sequence of a nucleic acid polymer.
• METHOD FOR DETERMINING SKIN ALLERGENICITY AND REAGENT FOR DETERMINING SKIN ALLERGENICITY
  申请人：FUJIFILM Corporation

  公开号：US20210181109A1

  公开（公告）日：2021-06-17

  An object of the present invention is to provide a method for determining skin allergenicity of a mixture containing two or more test substances, and a reagent for determining the skin allergenicity. The present invention provides a method for determining skin allergenicity, the method including causing a reaction between an organic compound that has at least one thiol group or amino group and emits fluorescence, and a mixture containing two or more test substances, and determining an amount of the organic compound after the reaction or an amount of a product of the reaction by an optical measurement using a fluorescence detector; and a reagent for determining skin allergenicity, the reagent including, as a measurement basis, an organic compound that has at least one thiol group or amino group and emits fluorescence, and being used for determining skin allergenicity of a mixture containing two or more test substances by an optical measurement using a fluorescence detector.
• US4079075A
  申请人：——

  公开号：US4079075A

  公开（公告）日：1978-03-14
• US9556353B2
  申请人：——

  公开号：US9556353B2

  公开（公告）日：2017-01-31