7-(3-nitrophenyl)-7H-bis-[1]benzopyrano[4,3-b:3',4'-c]pyran-6,8-dione | 64191-26-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: 7-(3-nitrophenyl)-7H-bis-[1]benzopyrano[4,3-b:3',4'-c]pyran-6,8-dione
• 英文别名: 3,3'-(3-nitrobenzylidene)-4,4'-epoxydicoumarin；7-(3-nitro-phenyl)-7H-pyrano[3,2-c;5,6-c'] dichromium ene-6,8-dione；7-(3-Nitro-phenyl)-7H-pyrano[3,2-c;5,6-c']dichromen-6,8-dion；7-(3-nitrophenyl)-6H,7H,8H-pyrano[3,2-c:5,6-c']dichromene-6,8-dione；13-(3-nitrophenyl)-2,10,16-trioxapentacyclo[12.8.0.03,12.04,9.017,22]docosa-1(14),3(12),4,6,8,17,19,21-octaene-11,15-dione
• CAS: 64191-26-0
• 化学式: C₂₅H₁₃NO₇
• 分子量: 439.381
• InChiKey: HLCMWIOYJYUOHW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  33
• 可旋转键数：
  1
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  108
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3,3'-((3-nitrophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) 在 乙酸酐 、 二甲基亚砜 作用下， 反应 0.03h， 以64%的产率得到7-(3-nitrophenyl)-7H-bis-[1]benzopyrano[4,3-b:3',4'-c]pyran-6,8-dione
  参考文献：
  名称：

  Reaction of Dimethyl Sulfoxide-Acetic Anhydride with 4-Hydroxy-coumarin and Its Derivatives Under Microwave Conditions

  摘要：

  在微波条件下合成的4-羟基香豆素和各种双香豆素在相同条件下用DMSO-Ac2O试剂处理，得到了不同的产物。文献中报告的常规反应方法与此进行了比较，并首次在最短时间内通过微波条件获得了更高的产量。

  DOI：

  10.14233/ajchem.2013.13483

文献信息

• P₂O₅/SiO₂as a New, Efficient and Reusable Catalyst for Preparation of 4,4′-Epoxydicoumarins Under Solvent-free Conditions
  作者：Liqiang Wu、Xiao Wang

  DOI：10.1155/2011/849795

  日期：——

  An efficient solvent-free procedure for the preparation of 4,4′-epoxydicoumarins via the ondensation of 4-hydroxycoumarin with aldehydes in the presence of catalytic amount of phosphorus pentoxide/silica gel at 110^°C is described. The advantages of this method are generality, high yields, short reaction times, ease of product isolation, low cost and ecologically friendly.

  通过在110°C下在磷酸五氧化硅胶的催化作用下，将4-羟基香豆素与醛缩合，制备4,4′-环氧基香豆素的高效无溶剂方法被描述。该方法的优点包括通用性高、产率高、反应时间短、产品分离容易、成本低且环保友好。
• DABCO-modified super-paramagnetic nanoparticles as an efficient and water-compatible catalyst for the synthesis of pyrano[3,2-<i>c</i>:5,6-<i>c</i>']dichromene-6,8-dione derivatives under mild reaction conditions
  作者：Zahra Heydari、Saeed Bahadorikhalili、Parviz Rashidi Ranjbar、Mohammad Mahdavi

  DOI：10.1002/aoc.4561

  日期：2018.12

  electron microscopy, vibrating‐sample magnetometer, thermogravimetric analysis, X‐ray photoelectron spectroscopy and Fourier‐transform infrared spectroscopy. This catalyst was used for the synthesis of pyrano[3,2‐c:5,6‐c']dichromene‐6,8‐dione derivatives. Several starting materials were used, and all of them led to the desired products in high isolated yields (19 examples). The catalyst also showed very

  本文基于超顺磁性氧化铁纳米粒子的固定化1,4-二氮杂双环[2.2.2]辛烷（DABCO），介绍了一种新型催化剂。对于催化剂的合成，首先通过（3-氯丙基）三甲氧基硅烷对二氧化硅-磁性氧化铁核壳纳米粒子进行功能化。然后，功能化的二氧化硅磁性氧化铁核壳纳米粒子与DABCO反应形成最终催化剂。通过扫描电子显微镜，振动样品磁力计，热重分析，X射线光电子能谱和傅里叶变换红外光谱对催化剂进行了表征。该催化剂用于合成吡喃并[3,2- c：5,6- c'] dichromene-6,8-dione衍生物。使用了几种起始原料，所有这些原料均以高分离产率获得了所需的产物（19个实例）。催化剂在反应中也显示出非常好的可重复使用性。
• Ma, Weiwei; Wang, Xiao; Yan, Fulin, Asian Journal of Chemistry, 2011, vol. 23, # 8, p. 3490 - 3492
  作者：Ma, Weiwei、Wang, Xiao、Yan, Fulin

  DOI：——

  日期：——
• Kocwa et al., Dissertationes Pharmaceuticae, 1959, vol. 11, p. 243,245
  作者：Kocwa et al.

  DOI：——

  日期：——
• Reaction of Dimethyl Sulfoxide-Acetic Anhydride with 4-Hydroxy-coumarin and Its Derivatives Under Microwave Conditions
  作者：Saima Qadir、Khaliquz Zaman Khan、Arif Jan

  DOI：10.14233/ajchem.2013.13483

  日期：——

  4-Hydroxycoumarin and various biscoumarins synthesized under microwave conditions were treated with the DMSO-Ac2O reagent under the same conditions to yield different products. A comparative account of the reactions with conventional procedure, as reported in literature, has been drawn and improved yields have been obtained in minimum time under microwave conditions for the first time.

  在微波条件下合成的4-羟基香豆素和各种双香豆素在相同条件下用DMSO-Ac2O试剂处理，得到了不同的产物。文献中报告的常规反应方法与此进行了比较，并首次在最短时间内通过微波条件获得了更高的产量。