6-乙酰氧基二氢茶螺烷 | 57967-74-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 中文名称: 6-乙酰氧基二氢茶螺烷
• 中文别名: (2α,5α(S*))-2,6,10,10-四甲基-1-氧杂螺(4.5)癸-6-基乙酸酯
• 英文名称: 2,6,10,10-tetramethyl-1-oxa-spiro[4.5]dec-6-yl acetate
• 英文别名: 6-Acetoxydihydrotheaspirane；(2,6,10,10-tetramethyl-1-oxaspiro[4.5]decan-6-yl) acetate
• CAS: 57967-74-5；57893-27-3；72541-09-4；57967-72-3；57967-73-4
• 化学式: C₁₅H₂₆O₃
• 分子量: 254.37
• InChiKey: LTAWGWRPOGXHBD-UHFFFAOYSA-N

物化性质

• 物理描述：
  Crystalline solid; Fermented, earthy, spice-like aroma
• 溶解度：
  Soluble in fats; insoluble in water

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,6,10,10-tetramethyl-1-oxaspiro[4.5]decan-6-ol 、 硫酸 、 乙酰氯 以 乙醇 、 水 、 N,N-二甲基苯胺 为溶剂， 生成 6-乙酰氧基二氢茶螺烷
  参考文献：
  名称：

  Esters of certain tetramethyl and pentamethyl-1-oxa-spiro [4-5]

  摘要：

  Spirane衍生物中的大部分都是新的，可用作制造香水和带香产品的气味改良成分，以及用于制造人造香料或为食品、动物饲料、饮料、制药制剂和烟草制品调味的味道改良成分。本发明涉及制备所述Spirane衍生物的方法。

  公开号：

  US04014905A1

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• [EN] ARTHROPOD CONTROLLING COMPOSITION<br/>[FR] COMPOSITION DE LUTTE CONTRE LES ARTHROPODES
  申请人：FIRMENICH & CIE

  公开号：WO2020239980A1

  公开（公告）日：2020-12-03

  The present invention relates to an arthropod controlling composition comprising a compound according to formula (I), methods and uses to control arthropods as well as arthropod controlling articles comprising the same.

  本发明涉及一种包括根据式(I)的化合物的节肢动物控制组合物，以及用于控制节肢动物的方法和用途，以及包含相同化合物的节肢动物控制物品。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• [EN] PHOTOSENSITIVE MICROCAPSULES<br/>[FR] MICROCAPSULES PHOTOSENSIBLES
  申请人：PROCTER & GAMBLE INT OPERATIONS SA

  公开号：WO2019030393A1

  公开（公告）日：2019-02-14

  A photosensitive microcapsule having a shell encapsulating a core material. The core material can comprise a benefit agent and the shell can comprise a photosensitive polymer. The photosensitive polymer can include one or more photosensitive moieties having a substituted amine and a 1,3 dione moiety. The core material can be released from the photosensitive microcapsule upon exposure to an electromagnetic radiation field selected from the group consisting of infrared radiation, visible light, ultraviolet radiation and mixtures thereof.

  一种具有光敏感性的微胶囊，其壳包覆着一个核心材料。核心材料可以包含一种益处剂，而壳可以包含一种光敏感性聚合物。光敏感性聚合物可以包括一个或多个具有取代胺和1,3-二酮基团的光敏感基团。核心材料可以在暴露于红外辐射、可见光、紫外辐射和其混合物中选择的电磁辐射场下从光敏感微胶囊中释放。
• Spirane derivatives
  申请人：Firmenich SA

  公开号：US04174327A1

  公开（公告）日：1979-11-13

  Spirane derivatives, most of them are new, useful as odor-modifying ingredients for manufacturing perfumes and perfumed products, and as flavor-modifying ingredients for the manufacture of artificial flavors of for flavoring foodstuffs, animal feeds, beverages, pharmaceutical preparations and tobacco products. Process for preparing said spirane derivatives.

  Spirane衍生物大多是新的，可用作制造香水和带香产品的气味修饰成分，以及用于制造人造香味或为食品、动物饲料、饮料、药品制剂和烟草制品调味的口味修饰成分。制备该Spirane衍生物的过程。