3-(1,3-benzodioxol-5-yl)-11-(4-hydroxy-3,5-dimethoxyphenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 3-(1,3-benzodioxol-5-yl)-11-(4-hydroxy-3,5-dimethoxyphenyl)-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one
• 英文别名: 9-(1,3-benzodioxol-5-yl)-6-(4-hydroxy-3,5-dimethoxyphenyl)-5,6,8,9,10,11-hexahydrobenzo[b][1,4]benzodiazepin-7-one
• 化学式: C₂₈H₂₆N₂O₆
• mdl: MFCD01874776
• 分子量: 486.5
• InChiKey: RCAUWRILWVSLSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  36
• 可旋转键数：
  4
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  98.3
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Small Molecule Inhibitors of RNA Silencing
  申请人：Ding Shou-Wei

  公开号：US20120077804A1

  公开（公告）日：2012-03-29

  The present invention provides compositions and formulations that contain active compounds as RNAi inhibitors. These compositions and formulations are useful for controlling insects and pests including mosquitoes and agricultural pests.
• SMALL MOLECULE INHIBITORS OF RNA SILENCING
  申请人：The Regents of the University of California

  公开号：US20150010493A1

  公开（公告）日：2015-01-08

  The present invention provides compositions and formulations that contain active compounds as RNAi inhibitors. These compositions and formulations are useful for controlling insects and pests including mosquitoes and agricultural pests.
• [EN] SMALL MOLECULE INHIBITORS OF RNA SILENCING<br/>[FR] INHIBITEURS À PETITE MOLÉCULE DE SILENÇAGE DE L'ARN
  申请人：UNIV CALIFORNIA

  公开号：WO2009018084A1

  公开（公告）日：2009-02-05

  The present invention provides compositions and formulations that contain active compounds as RNAi inhibitors. These compositions and formulations are useful for controlling insects and pests including mosquitoes and agricultural pests.