3-(Azidomethyl)-2-methylpent-1-ene

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: 3-(Azidomethyl)-2-methylpent-1-ene
• 英文别名: 3-(azidomethyl)-2-methylpent-1-ene
• 化学式: C7H13N3
• 分子量: 139.2
• InChiKey: VOMRJKASMJOGSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  14.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS
  申请人：Blaskovich Mark Arnold Thomas

  公开号：US20090221557A1

  公开（公告）日：2009-09-03

  The present invention provides compounds of Formula (I) that are useful for modulating the biological activity of the melanocortin-5 receptor (MC5R). Compounds of this invention can be used to treat diseases and/or conditions in which downregulation of MC5R is beneficial. Such diseases and/or conditions include, but are not limited to, acne, seborrhea, seborrheic dermatitis, cancer, and inflammatory diseases.

  本发明提供了一种公式（I）的化合物，该化合物对调节黑色素皮质素-5受体（MC5R）的生物活性有用。本发明的化合物可用于治疗下调MC5R有益的疾病和/或症状。这些疾病和/或症状包括但不限于痤疮、脂溢性皮炎、皮肤癌和炎症性疾病。
• 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5-RECEPTOR ANTAGONISTS
  申请人：Blaskovich Mark Arnold Thomas

  公开号：US20110263572A1

  公开（公告）日：2011-10-27

  The present invention provides compounds of Formula (I) that are useful for modulating the biological activity of the melanocortin-5 receptor (MC5R). Compounds of this invention can be used to treat diseases and/or conditions in which downregulation of MC5R is beneficial. Such diseases and/or conditions include, but are not limited to, acne, seborrhea, seborrheic dermatitis, cancer, and inflammatory diseases.

  本发明提供了公式(I)的化合物，它们对调节黑素细胞激素-5受体(MC5R)的生物活性有用。本发明的化合物可用于治疗下调MC5R有益的疾病和/或状况。这些疾病和/或状况包括但不限于痤疮、脂溢性皮炎、皮脂溢出、癌症和炎症性疾病。
• US8008291B2
  申请人：——

  公开号：US8008291B2

  公开（公告）日：2011-08-30
• US8343958B2
  申请人：——

  公开号：US8343958B2

  公开（公告）日：2013-01-01
• [EN] 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS<br/>[FR] ANTAGONISTES 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE DU RÉCEPTEUR 5 DE LA MÉLANOCORTINE
  申请人：MIMETICA PTY LTD

  公开号：WO2009105823A1

  公开（公告）日：2009-09-03

  The present invention provides compounds of Formula (I) that are useful for modulating the biological activity of the melanocortin-5 receptor (MC5R). Compounds of this invention can be used to treat diseases and/or conditions in which downregulation of MC5R is beneficial. Such diseases and/or conditions include, but are not limited to, acne, seborrhea, seborrheic dermatitis, cancer, and inflammatory diseases.