2-chloro-3-(di-1H-indol-3-ylmethyl)phenol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-chloro-3-(di-1H-indol-3-ylmethyl)phenol
• 英文别名: 3-[bis(1H-indol-3-yl)methyl]-2-chlorophenol
• 化学式: C₂₃H₁₇ClN₂O
• 分子量: 372.8
• InChiKey: ZEQTYNQTJQBAKI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  51.8
• 氢给体数：
  3
• 氢受体数：
  1

文献信息

• NR4A1 LIGANDS, PHARMACEUTICAL COMPOSITIONS, AND RELATED METHODS OF USE
  申请人：The Texas A&M University System

  公开号：US20200239448A1

  公开（公告）日：2020-07-30

  NR4A1 ligands, pharmaceutical compositions including the NR4A1 ligands, and related methods of use are described. Methods of treating a disease or condition in an individual treatable by modulation of NR4A1 activity, comprising administering to the individual a therapeutically effective amount of a compound or a pharmaceutical composition described herein.
• [EN] NR4A1 LIGANDS, PHARMACEUTICAL COMPOSITIONS, AND RELATED METHODS OF USE<br/>[FR] LIGANDS DE NR4A1, COMPOSITIONS PHARMACEUTIQUES ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：TEXAS A & M UNIV SYS

  公开号：WO2019032902A1

  公开（公告）日：2019-02-14

  NR4A1 ligands, pharmaceutical compositions including the NR4A1 ligands, and related methods of use are described. Methods of treating a disease or condition in an individual treatable by modulation of NR4A1 activity, comprising administering to the individual a therapeutically effective amount of a compound or a pharmaceutical composition described herein.