2-(6,7,8,9-Tetrahydropyrido[3,2-b]indol-5-yl)acetic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2-(6,7,8,9-Tetrahydropyrido[3,2-b]indol-5-yl)acetic acid
• 英文别名: 2-(6,7,8,9-tetrahydropyrido[3,2-b]indol-5-yl)acetic acid
• 化学式: C₁₃H₁₄N₂O₂
• 分子量: 230.26
• InChiKey: OVYHQQFRZMNIKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• AZAINDOLE ACETIC ACID DERIVATIVES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR MODULATORS
  申请人：ACTELION PHARMACEUTICALS LTD

  公开号：US20170129884A1

  公开（公告）日：2017-05-11

  The present invention relates to azaindole acetic acid derivatives of formula (I), wherein R 1 and R 2 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D 2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
• US9850241B2
  申请人：——

  公开号：US9850241B2

  公开（公告）日：2017-12-26