oxamate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: oxamate
• 化学式: C₂H₂NO₃
• 分子量: 88.0428
• InChiKey: SOWBFZRMHSNYGE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  83.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  carbamoyl phosphate 、 oxamate 生成 Oxalurate 、 H3PO4
  参考文献：
  名称：

  OXAMIC TRANSCARBAMYLASE OF STREPTOCOCCUS ALLANTOICUS

  摘要：

  Bojanowski，R.（伊利诺伊大学厄巴纳分校），Elizabeth Gaudy，R.C. Valentine和R.S. Wolfe。Streptococcus allantoicus的氧化羰酰胺酶。J. Bacteriol. 87：75-80。1964年。——开发了一种改进的比色法测定羰酰氧胺酯酶活性的方法，可精确测量氧化羰酰胺酶的活性。在pH 8.3至8.7的范围内，活性最大。2.5×10-3 m Mg ++或Mn ++满足阳离子要求。羰酰氧胺酸的磷酸解作用的平衡常数为1.6，相应的负自由能变化为-285卡路里/摩尔。

  DOI：

  10.1128/jb.87.1.75-80.1964

文献信息

• WEATHERABLE POLYCARBONATES COMPRISING OXANILIDE STRUCTURAL UNITS, METHOD, AND ARTICLES MADE THEREFROM
  申请人：General Electric Company

  公开号：US20020161164A1

  公开（公告）日：2002-10-31

  In one embodiment the present invention is a polycarbonate comprising structural units derived from at least one dihydric phenol, a carbonate precursor, and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof. In another embodiment the present invention is a method for making a polycarbonate comprising structural units derived from at least one dihydric phenol and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof, which comprises the step of contacting under reactive conditions at least one dihydric phenol, a carbonate precursor, and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof. In still another embodiment the present invention is an article comprising a polycarbonate comprising oxanilide structural units. In still another embodiment the present invention is a method for making a symmetrical or unsymmetrical oxanilide-comprising dihydric phenol which comprises the step of contacting at least one aromatic amine bearing a hydroxy group with a diaryl oxalate or a dialkyl oxalate bearing alkyl groups each substituted with at least one electron-withdrawing group. In still another embodiment the present invention is a method for making an oxamate-comprising monohydric phenol which comprises the step of contacting an aromatic amine bearing a hydroxy group with a diaryl oxalate or a dialkyl oxalate bearing alkyl groups each substituted with at least one electron-withdrawing group.

  在一种实施方式中，本发明是一种聚碳酸酯，其包括从至少一种双酚、碳酸酯前体和选自包括含氧杂环苯酰亚胺化合物、含氧杂环酰胺化合物和其混合物的至少一种成员中导出的结构单元。在另一种实施方式中，本发明是一种制备聚碳酸酯的方法，其包括在反应条件下接触至少一种双酚、碳酸酯前体和选自包括含氧杂环苯酰亚胺化合物、含氧杂环酰胺化合物和其混合物的至少一种成员。在另一种实施方式中，本发明是一种包括含氧杂环苯酰亚胺结构单元的聚碳酸酯制品。在另一种实施方式中，本发明是一种制备对称或非对称含氧杂环苯酰亚胺双酚的方法，其包括将至少一种带有羟基的芳香胺与带有至少一个电子吸引基取代的烷基基团的二芳酸酯或二烷基草酸酯接触。在另一种实施方式中，本发明是一种制备含氧杂环酰胺单酚的方法，其包括将带有羟基的芳香胺与带有至少一个电子吸引基取代的烷基基团的二芳酸酯或二烷基草酸酯接触。
• Weatherable polycarbonates comprising oxanilide structural units, method, and articles made therefrom
  申请人：General Electric Company

  公开号：US06462168B1

  公开（公告）日：2002-10-08

  In one embodiment the present invention is a polycarbonate comprising structural units derived from at least one dihydric phenol, a carbonate precursor, and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof. In another embodiment the present invention is a method for making a polycarbonate comprising structural units derived from at least one dihydric phenol and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof, which comprises the step of contacting under reactive conditions at least one dihydric phenol, a carbonate precursor, and at least one member selected from the group consisting of an oxanilide-comprising compound, an oxamate-comprising compound, and mixtures thereof. In still another embodiment the present invention is an article comprising a polycarbonate comprising oxanilide structural units. In still another embodiment the present invention is a method for making a symmetrical or unsymmetrical oxanilide-comprising dihydric phenol which comprises the step of contacting at least one aromatic amine bearing a hydroxy group with a diaryl oxalate or a dialkyl oxalate bearing alkyl groups each substituted with at least one electron-withdrawing group. In still another embodiment the present invention is a method for making an oxamate-comprising monohydric phenol which comprises the step of contacting an aromatic amine bearing a hydroxy group with a diaryl oxalate or a dialkyl oxalate bearing alkyl groups each substituted with at least one electron-withdrawing group.

  在一种实施方式中，本发明是一种聚碳酸酯，其包含源自至少一种双酚，碳酸酯前体和至少从包括含氧代苯并咪唑化合物，含氧代甲酰胺化合物和它们的混合物中选择的一种成员的结构单元。在另一种实施方式中，本发明是一种制备聚碳酸酯的方法，其包含源自至少一种双酚和至少从包括含氧代苯并咪唑化合物，含氧代甲酰胺化合物和它们的混合物中选择的一种成员的结构单元，其中包括在反应条件下接触至少一种双酚，碳酸酯前体和至少从包括含氧代苯并咪唑化合物，含氧代甲酰胺化合物和它们的混合物中选择的一种成员。在另一种实施方式中，本发明是一种包含含氧代苯并咪唑结构单元的聚碳酸酯的制品。在另一种实施方式中，本发明是一种制备对称或非对称含氧代苯并咪唑的双酚的方法，其中包括将至少一种带有羟基的芳香胺与一种二芳基草酸酯或一种带有至少一个电子吸引基的烷基基团的二烷基草酸酯接触。在另一种实施方式中，本发明是一种制备含氧代甲酰胺的单酚的方法，其中包括将带有羟基的芳香胺与二芳基草酸酯或带有至少一个电子吸引基的烷基基团的二烷基草酸酯接触。
• Biochemical and structural characterization of<i>Klebsiella pneumoniae</i>oxamate amidohydrolase in the uric acid degradation pathway
  作者：Katherine A. Hicks、Steven E. Ealick

  DOI：10.1107/s2059798316007099

  日期：2016.6.1

  α subunit and a 20 kDa β subunit. Here, the structure of HpxW is presented and the substrate complex is modeled. In addition, the steady‐state kinetics of this enzyme and two active‐site variants were characterized. These structural and biochemical studies provide further insight into this class of enzymes and allow a mechanism for catalysis consistent with other members of the Ntn‐hydrolase superfamily

  来自无处不在的病原菌肺炎克雷伯菌的HpxW在草酸酯的形成中下游参与了新的尿酸降解途径。特别是，HpxW是草酸盐酰胺酰水解酶，它催化草酸盐转化为草酸盐，并且是Ntn-水解酶超家族的成员。HpxW由无活性的前体自动加工形成异二聚体，从而产生35.5 kDaα亚基和20 kDaβ亚基。在此，介绍了HpxW的结构并对基质复合物进行了建模。此外，还表征了该酶和两个活性位点变体的稳态动力学。这些结构和生化研究为此类酶提供了进一步的见解，并提出了与Ntn-水解酶超家族其他成员一致的催化机制。
• Crystal growth and structure of La2(C2O4)3 9.5H2O
  作者：A. Michaelides、S. Skoulika、A. Aubry

  DOI：10.1016/0025-5408(88)90166-3

  日期：1988.4

  Abstract Single crystals of La 2 (C 2 O 4 ) 3 9.5H 2 O have been grown in a silica gel by “in situ” generation of oxalic acid. Crystal structure analysis has been carried out in order to complete the results given by Ollendorff and Weigel in a preliminary report (Inorg. Nucl. Chem. Letters 5, 263 (1969)). The value of 9.5 water molecules was that indicated by both thermogravimetry and X-ray diffraction

  摘要 La 2 (C 2 O 4 ) 3 9.5H 2 O 单晶已通过“原位”生成草酸在硅胶中生长。进行了晶体结构分析以完成 Ollendorff 和 Weigel 在初步报告中给出的结果（Inorg. Nucl. Chem. Letters 5, 263 (1969)）。9.5个水分子的值是由热重法和X射线衍射表明的。