N-{1-[1-(2,4-dichlorophenyl)cyclopropyl]ethyl}-2-chloropyrazine-3-carboxamide | 951017-43-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: N-{1-[1-(2,4-dichlorophenyl)cyclopropyl]ethyl}-2-chloropyrazine-3-carboxamide
• 英文别名: 3-chloro-N-[1-[1-(2,4-dichlorophenyl)cyclopropyl]ethyl]pyrazine-2-carboxamide
• CAS: 951017-43-9
• 化学式: C₁₆H₁₄Cl₃N₃O
• 分子量: 370.666
• InChiKey: IGDWEUZKPXGQME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  54.9
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-[1-(2,4-dichlorophenyl)cyclopropyl]ethanone 在 镍 盐酸 、 4-二甲氨基吡啶 、 盐酸羟胺 、 氢气 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三乙胺 作用下， 以 乙醇 、 甲基叔丁基醚 、 氯仿 、 乙酸乙酯 为溶剂， 反应 50.0h， 生成 N-{1-[1-(2,4-dichlorophenyl)cyclopropyl]ethyl}-2-chloropyrazine-3-carboxamide
  参考文献：
  名称：

  EP1997800

  摘要：

  公开号：

文献信息

• N-2-(Hetero)Arylethylcarboxamide Derivative, and Pest-Controlling Agent Comprising the Same
  申请人：Oda Masatsugu

  公开号：US20110136831A1

  公开（公告）日：2011-06-09

  An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R 1 and R 2 are each independently a hydrogen atom etc., R 3 and R 4 are each independently a hydrogen atom etc., each Y is independently a halogen atom; a (C 1 -C 6 )alkyl group optionally substituted by halogen atom(s) etc., n is an integer of 1 to 5, A is a specific substituted cyclic group, E is C—H; C—Y (Y is as defined above); or a nitrogen atom, a salt thereof, and a pest controlling agent containing the derivative or salt as an active ingredient show superior performance as compared to the prior art technique, and are is useful particularly as plant disease controlling agents or nematocides having a broad control spectrum at a low dose.

  一种N-2-(杂)芳基乙基羧酰胺衍生物，其化学式表示为(I)，其中R1和R2分别独立地表示氢原子等，R3和R4分别独立地表示氢原子等，每个Y独立地表示卤原子；一种(C1-C6)烷基，该烷基可选择地被卤原子等取代等，n为1至5的整数，A是一种特定的取代环状基团，E为C—H；C—Y（其中Y如上所定义）；或氮原子，其盐，以及含有该衍生物或盐作为活性成分的杀虫剂与先前技术相比表现出卓越性能，并且特别适用于具有广泛控制光谱的植物病害控制剂或线虫剂，剂量低。
• N-2-(hetero)arylethylcarboxamide derivative, and pest-controlling agent comprising the same
  申请人：Oda Masatsugu

  公开号：US08378114B2

  公开（公告）日：2013-02-19

  An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R1 and R2 are each independently a hydrogen atom etc., R3 and R4 are each independently a hydrogen atom etc., each Y is independently a halogen atom; a (C1-C6)alkyl group optionally substituted by halogen atom(s) etc., n is an integer of 1 to 5, A is a specific substituted cyclic group, E is C—H; C—Y (Y is as defined above); or a nitrogen atom, a salt thereof, and a pest controlling agent containing the derivative or salt as an active ingredient show superior performance as compared to the prior art technique, and are is useful particularly as plant disease controlling agents or nematocides having a broad control spectrum at a low dose.

  化合物I的结构式如下：N-2-(杂)芳基乙基甲酰胺衍生物，其中R1和R2各自独立地为氢原子等，R3和R4各自独立地为氢原子等，每个Y独立地为卤素原子；一种（C1-C6）烷基，可选地被卤素原子等取代，n是1至5的整数，A是一种特定的取代环状基团，E是C-H；C-Y（其中Y如上定义）；或氮原子，其盐，以及含有该衍生物或盐作为活性成分的杀虫剂与先前的技术相比表现出优越性能，并且在低剂量下具有广泛控制光谱，特别适用于作为植物病害控制剂或线虫灭生剂。
• N-2-(HETERO)ARYLETHYLCARBOXAMIDE DERIVATIVE, AND PEST-CONTROLLING AGENT COMPRISING THE SAME
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP1997800A1

  公开（公告）日：2008-12-03

  An N-2-(hetero)arylethylcarboxamide derivative represented by the formula (I) wherein R1 and R2 are each independently a hydrogen atom etc., R3 and R4 are each independently a hydrogen atom etc., each Y is independently a halogen atom; a (C1-C6)alkyl group optionally substituted by halogen atom(s) etc., n is an integer of 1 to 5, A is a specific substituted cyclic group, E is C-H; C-Y (Y is as defined above); or a nitrogen atom, a salt thereof, and a pest controlling agent containing the derivative or salt as an active ingredient show superior performance as compared to the prior art technique, and are useful particularly as plant disease controlling agents or nematocides having a broad control spectrum at a low dose.

  由式 (I) 代表的 N-2-(杂)芳基乙基甲酰胺衍生物 其中 R1 和 R2 各自独立地为氢原子等，R3 和 R4 各自独立地为氢原子等，Y 各自独立地为卤素原子、任选被卤素原子等取代的(C1-C6)烷基、n 是 1 至 5 的整数，A 是特定取代的环状基团，E 是 C-H；C-Y（Y 如上文所定义）；或氮原子，其盐和含有该衍生物或盐作为活性成分的害虫防治剂与现有技术相比表现出更优越的性能，尤其可用作植物病害防治剂或杀线虫剂，具有低剂量、广谱防治的特点。
• US8378114B2
  申请人：——

  公开号：US8378114B2

  公开（公告）日：2013-02-19
• EP1997800
  申请人：——

  公开号：——

  公开（公告）日：——