1-(3,3-Diethoxypropyl)-2-[3-[1-(3,3-diethoxypropyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethylindole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-(3,3-Diethoxypropyl)-2-[3-[1-(3,3-diethoxypropyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethylindole
• 英文别名: 1-(3,3-diethoxypropyl)-2-[3-[1-(3,3-diethoxypropyl)-3,3-dimethylindol-1-ium-2-yl]prop-2-enylidene]-3,3-dimethylindole
• 化学式: C37H53N2O4+
• 分子量: 589.8
• InChiKey: NPWATMPTZAHMHT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  43
• 可旋转键数：
  16
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  43.2
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• A CYANINE-BASED PROBE\TAG-PEPTIDE PAIR FOR FLUORESCENCE PROTEIN IMAGING AND FLUORESCENCE PROTEIN IMAGING METHODS
  申请人：BATTELLE MEMORIAL INSTITUTE

  公开号：EP2152810A1

  公开（公告）日：2010-02-17
• A Cyanine-based probe\tag-peptide pair for fluorescence protein imaging and fluorescence protein imaging methods
  申请人：Mayer-Cumblidge M. Uljana

  公开号：US20080254546A1

  公开（公告）日：2008-10-16

  A molecular probe comprises two arsenic atoms and at least one cyanine based moiety. A method of producing a molecular probe includes providing a molecule having a first formula, treating the molecule with HgOAc, and subsequently transmetallizing with AsCl 3 . The As is liganded to ethanedithiol to produce a probe having a second formula. A method of labeling a peptide includes providing a peptide comprising a tag sequence and contacting the peptide with a biarsenical molecular probe. A complex is formed comprising the tag sequence and the molecular probe. A method of studying a peptide includes providing a mixture containing a peptide comprising a peptide tag sequence, adding a biarsenical probe to the mixture, and monitoring the fluorescence of the mixture.
• Cyanine-Based Probe\Tag-Peptide Pair Fluorescence Protein Imaging and Fluorescence Protein Imaging Methods
  申请人：Mayer-Cumblidge M. Uljana

  公开号：US20100216182A1

  公开（公告）日：2010-08-26

  A molecular probe comprises two arsenic atoms and at least one cyanine based moiety. A method of producing a molecular probe includes providing a molecule having a first formula, treating the molecule with HgOAc, and subsequently transmetallizing with AsCl 3 . The As is liganded to ethanedithiol to produce a probe having a second formula. A method of labeling a peptide includes providing a peptide comprising a tag sequence and contacting the peptide with a biarsenical molecular probe. A complex is formed comprising the tag sequence and the molecular probe. A method of studying a peptide includes providing a mixture containing a peptide comprising a peptide tag sequence, adding a biarsenical probe to the mixture, and monitoring the fluorescence of the mixture.
• US7776999B2
  申请人：——

  公开号：US7776999B2

  公开（公告）日：2010-08-17
• US8354499B2
  申请人：——

  公开号：US8354499B2

  公开（公告）日：2013-01-15