2-(acetoacetyloxy)-propionic acid 2,2,6,6-tetramethyl-4-piperidyl ester | 216692-35-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 2-(acetoacetyloxy)-propionic acid 2,2,6,6-tetramethyl-4-piperidyl ester
• 英文别名: [1-oxo-1-(2,2,6,6-tetramethylpiperidin-4-yl)oxypropan-2-yl] 3-oxobutanoate
• CAS: 216692-35-2
• 化学式: C₁₆H₂₇NO₅
• 分子量: 313.394
• InChiKey: FSZPDUNNSIAVBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  81.7
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  lactic acid 2,2,6,6-tetramethyl-4-piperidyl ester 、 2,2,6-三甲基-4H-1,3-二英-4-酮 以 甲苯 为溶剂， 反应 3.0h， 生成 2-(acetoacetyloxy)-propionic acid 2,2,6,6-tetramethyl-4-piperidyl ester
  参考文献：
  名称：

  &bgr;-ketoesters for use as polymer stabilizers

  摘要：

  -Keto酯及其从醇类或多元醇类中得到的烯胺适用于稳定聚合物，其化学式为：A[(O—CHR4—Z—CHR5)m—O—CO—CHR1—CO—R3]n和A[(O—CHR4—Z—CHR5)m—O—CO—CR1═C(—NHR2)—R3]n，其中：A是从羟基烷酸酯、糖及其糖苷、糖醇、糖酸及其酯、寡糖中选择的醇或多元醇的残基；m是从0到6的整数；n是从1到多元醇中羟基总数的数字；R1是氢、C1-C8烷基、C3-C8烯基或环烷基（烷基）或C6-C8芳基或芳基烷基；R2是氢、C1-C6烷基、C2-C6羟基烷基或C3-C6烯基；R3是C1-C18烷基、烷氧基或烷基氨基、C3-C18烯基、烷酰甲基、烷氧羰基甲基或环烷基（烷基）、C6-C18芳基、芳氧基、芳基氨基、芳基烷基、芳基烷氧基或芳基烷基氨基，或C8-C18芳酰甲基、芳氧羰基甲基或芳基碳酰胺甲基；R4和R5独立地是氢或甲基；Z是直接键、CH2、CHOH、CH—O—CO—CHR1—CO—R3或O—CO—CR1═C(—NHR2)—R3。

  公开号：

  US06355713B1

文献信息

• B-ketoesters for use as polymer stabilisers
  申请人：AKCROS CHEMICALS

  公开号：EP0881253A1

  公开（公告）日：1998-12-02

  β-Ketoesters derived from alcohols or polyols, which are natural product or can be obtained from natural products by fermentation processes and optional subsequent oxidation or reduction, are suitable for stabilising polymers, The ketoesters are represented by formula 1:         A[(O-CHR4-Z-CHR5)m-O-CO-CR1R2-CO-R3]n wherein: Ais the residue of an alcohol or polyol selected from hydroxyalkanoic acid esters, sugars and their glycosides, sugar alcohols, sugar acids and their esters, and oligosaccharides; mis an integer number from 0 up to 6; nis a number from 1 up to the total number of hydroxyl groups in the polyol; R1is hydrogen, C1-C8 alkyl, C3-C8 alkenyl or cycloalkyl(alkyl) or C6-C8 aryl or aralkyl; R2is hydrogen, C1-C8 alkyl or C3-C8 alkenyl; R3is C1-C18 alkyl, alkoxy or alkylamino, C3-C18 alkenyl, alkanoylmethyl, alkoxycarbonylmethyl or cycloalkyl(alkyl), C6-C18 aryl, aryloxy, arylamino, aralkyl, aralkoxy or aralkylamino, or C8-C18 aroylmethyl, aryloxycarbonylmethyl or arylcarbamoylmethyl; R4 and R5are independently hydrogen or methyl; and Zis a direct bond, CH2, CHOH or CH-O-CO-CR1R2-CO-R3.

  来源于醇或多元醇的β-酮酸酯是天然产物，或者可以通过发酵过程和可选的氧化或还原获得，适用于稳定聚合物。酮酸酯由公式1表示： A[(O-CHR4-Z-CHR5)m-O-CO-CR1R2-CO-R3]n，其中： A是从羟基烷酸酯，糖及其糖苷，糖醇，糖酸及其酯，寡糖中选择的醇或多元醇的残留物; m是从0到6的整数; n是从1到多元醇中羟基总数的数字; R1是氢，C1-C8烷基，C3-C8烯基或环烷基（烷基）或C6-C8芳基或芳基烷基; R2是氢，C1-C8烷基或C3-C8烯基; R3是C1-C18烷基，烷氧基或烷基氨基，C3-C18烯基，烷酰甲基，烷氧羰基甲基或环烷基（烷基），C6-C18芳基，芳氧基，芳基氨基，芳基烷基，芳基烷氧基或芳基烷基氨基，或C8-C18芳香基甲基，芳氧羰基甲基或芳基氨基甲基; R4和R5独立地是氢或甲基; Z是直接键，CH2，CHOH或CH-O-CO-CR1R2-CO-R3。
• US6355713B1
  申请人：——

  公开号：US6355713B1

  公开（公告）日：2002-03-12
• &bgr;-ketoesters for use as polymer stabilizers
  申请人：Akcros, Chemicals

  公开号：US06355713B1

  公开（公告）日：2002-03-12

  &bgr;-Ketoesters and their enamines derived from alcohols or polyols are suitable for stabilizing polymers, and are represented by formulae: A[(O—CHR4—Z—CHR5)m—O—CO—CHR1—CO—R3]n and A[(O—CHR4—Z—CHR5)m—O—CO—CR1═C(—NHR2)—R3]n, wherein: A is the residue of an alcohol or polyol selected from hydroxyalkanoic acid esters, sugars and their glycosides, sugar alcohols, sugar acids and their esters, and oligosaccharides; m is an integer number from 0 up to 6; n is a number from 1 up to the total number of hydroxyl groups in the polyol; R1 is hydrogen, C1-C8 alkyl, C3-C8 alkenyl or cycloalkyl (alkyl) or C6-C8 aryl or aralkyl; R2 is hydrogen, C1-C6 alkyl, C2-C6 hydroxyalkyl or C3-C6 alkenyl; R3 is C1-C18 alkyl, alkoxy or alkylamino, C3-C18 alkenyl, alkanoylmethyl, alkoxycarbonylmethyl or cycloalkyl(alkyl), C6-C18 aryl, aryloxy, arylamino, aralkyl, aralkoxy or aralkylamino, or C8-C18 aroylmethyl, aryloxycarbonylmethyl or arylcarbamoylmethyl; R4 and R5 are independently hydrogen or methyl; and Z is a direct bond, CH2, CHOH, CH—O—CO—CHR1—CO—R3 or O—CO—CR1═C(—NHR2)—R3.

  -Keto酯及其从醇类或多元醇类中得到的烯胺适用于稳定聚合物，其化学式为：A[(O—CHR4—Z—CHR5)m—O—CO—CHR1—CO—R3]n和A[(O—CHR4—Z—CHR5)m—O—CO—CR1═C(—NHR2)—R3]n，其中：A是从羟基烷酸酯、糖及其糖苷、糖醇、糖酸及其酯、寡糖中选择的醇或多元醇的残基；m是从0到6的整数；n是从1到多元醇中羟基总数的数字；R1是氢、C1-C8烷基、C3-C8烯基或环烷基（烷基）或C6-C8芳基或芳基烷基；R2是氢、C1-C6烷基、C2-C6羟基烷基或C3-C6烯基；R3是C1-C18烷基、烷氧基或烷基氨基、C3-C18烯基、烷酰甲基、烷氧羰基甲基或环烷基（烷基）、C6-C18芳基、芳氧基、芳基氨基、芳基烷基、芳基烷氧基或芳基烷基氨基，或C8-C18芳酰甲基、芳氧羰基甲基或芳基碳酰胺甲基；R4和R5独立地是氢或甲基；Z是直接键、CH2、CHOH、CH—O—CO—CHR1—CO—R3或O—CO—CR1═C(—NHR2)—R3。