N-(acrylamido-3 propionyloxy) succinimide | 63406-06-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N-(acrylamido-3 propionyloxy) succinimide
• 英文别名: 2,5-Dioxopyrrolidin-1-yl N-acryloyl-beta-alaninate；(2,5-dioxopyrrolidin-1-yl) 3-(prop-2-enoylamino)propanoate
• CAS: 63406-06-4
• 化学式: C₁₀H₁₂N₂O₅
• 分子量: 240.216
• InChiKey: GYRWHEGKHHSVKC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  92.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N-(acrylamido-3 propionyloxy) succinimide 在 N,N'-二环己基碳二亚胺 作用下， 以 乙腈 为溶剂， 反应 36.0h， 生成 (acrylamido-3 propanamido)-3 N-phenyl propanamide
  参考文献：
  名称：

  Joyeau, Roger; Brown, Eric, Bulletin de la Societe Chimique de France, 1982, vol. 2, # 11/12, p. 391 - 394

  摘要：

  DOI：
• 作为产物：
  描述：

  N-羟基丁二酰亚胺 、 N-丙烯酰-β-丙氨酸 在 N,N'-二环己基碳二亚胺 作用下， 以 乙腈 为溶剂， 反应 15.0h， 生成 N-(acrylamido-3 propionyloxy) succinimide
  参考文献：
  名称：

  Joyeau, Roger; Brown, Eric, Bulletin de la Societe Chimique de France, 1982, vol. 2, # 11/12, p. 391 - 394

  摘要：

  DOI：

文献信息

• JOYEAU, R.;BROWN, E., BULL. SOC. CHIM. FRANCE, 1982, N 11-12, 391-394
  作者：JOYEAU, R.、BROWN, E.

  DOI：——

  日期：——
• Method for producing a biosensor
  申请人：Nishimi Taisei

  公开号：US20070258866A1

  公开（公告）日：2007-11-08

  An object of the present invention is to provide a biosensor comprising a hydrogel capable of immobilizing a physiologically active substance thereon, which can be produced conveniently by use of a safe material, and a method for producing the same. The present invention provides a method for producing a biosensor, which comprises bringing a polymer containing an activated carboxyl group into contact with a substrate surface coated with an organic layer having an amino group to thereby bind the polymer to the organic layer.
• Biosensor
  申请人：Ezoe Toshihide

  公开号：US20080038841A1

  公开（公告）日：2008-02-14

  It is an object of the present invention to provide a biosensor on which a large amount of protein can be immobilized and nonspecific adsorption is less likely to occur with the use of a SAM compound having high water solubility and good performance in terms of supply. The present invention provides a biosensor comprising a substrate on which a hydrophilic polymer having a reactive group capable of binding to a physiologically active substance is immobilized via a compound represented by the following formula (1), said compound at a concentration of 1 mM being dissolved in water at 25° C.: X-L-Y  (1) wherein X represents a group capable of binding to metal, L represents a linking group, and Y represents a functional group to which the hydrophilic polymer is bound.
• BIOSENSOR
  申请人：NISHIMI Taisei

  公开号：US20100221845A1

  公开（公告）日：2010-09-02

  One object of the present invention is to provide a biosensor and a production method therefor, by which hydrogel that enables immobilization of a physiologically active substance can be conveniently produced using safe raw materials. The present invention provides a biosensor which comprises a substrate having a metal layer on its surface, wherein a hydrophilic polymer having a reactive functional group capable of reacting with a hydroxyl group or an amino group of a physiologically active substance is bound to the metal layer directly or indirectly via an intermediate layer.
• METHOD FOR PRODUCING A BIOSENSOR
  申请人：FUJIFILM Corporation

  公开号：US20150024392A1

  公开（公告）日：2015-01-22

  An object of the present invention is to provide a biosensor comprising a hydrogel capable of immobilizing a physiologically active substance thereon, which can be produced conveniently by use of a safe material, and a method for producing the same. The present invention provides a method for producing a biosensor, which comprises bringing a polymer containing an activated carboxyl group into contact with a substrate surface coated with an organic layer having an amino group to thereby bind the polymer to the organic layer.