1,1,3,3,5,5-hexakis(4-(bromomethyl)phenoxy)cyclotriphosphazene | 82280-42-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1,3,3,5,5-hexakis(4-(bromomethyl)phenoxy)cyclotriphosphazene
• 英文别名: 2,2,4,4,6,6-Hexakis[4-(bromomethyl)phenoxy]-1,3,5-triaza-2lambda5,4lambda5,6lambda5-triphosphacyclohexa-1,3,5-triene；2,2,4,4,6,6-hexakis[4-(bromomethyl)phenoxy]-1,3,5-triaza-2λ5,4λ5,6λ5-triphosphacyclohexa-1,3,5-triene
• CAS: 82280-42-0
• 化学式: C₄₂H₃₆Br₆N₃O₆P₃
• 分子量: 1251.11
• InChiKey: ZEVWMFWRMYQPMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.1
• 重原子数：
  60
• 可旋转键数：
  18
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  92.5
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  1,1,3,3,5,5-hexakis(4-(bromomethyl)phenoxy)cyclotriphosphazene 在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以90%的产率得到1,1,3,3,5,5-hexakis(4-(azidomethyl)phenoxy)cyclotriphosphazene
  参考文献：
  名称：

  通过“点击化学”合成末端封端的A6树枝状聚合物和具有磷腈核的星形聚合物

  摘要：

  新型六臂和pyr（Pyr）封端的磷腈树枝状聚合物[N 3 P 3-（Pyr）6 ]和具有聚（ε-己内酯）（PCL）臂的星形聚合物[N 3 P 3-（PCL- Pyr）通过两个系列的反应制备[ 6 ]。在这些系列中，从六羟基官能磷腈衍生物（N 3 P 3-（OH）6）开始使用了先核方法。在ε-己内酯的开环聚合反应中用作引发剂以制备六臂PCL星型聚合物（N 3 P 3-（PCL- OH）6）。N 3 P 3-（OH）6和N 3 P 3-（PCL- OH）6的羟基官能度随后成功地转化为溴化物和叠氮化物。叠氮化物官能树状大分子前体（N 3 P 3-（N 3）6）和星形聚合物（N 3 P 3-（PCL- N 3）6的进一步端基修饰）是在最后一步通过叠氮化物官能团和1-乙炔基1之间的Cu（I）催化的点击反应定量实现的。此外，the封端的磷腈树枝状聚合物和星形聚合物用于多壁碳纳米管的非共价官能化。©2011

  DOI：

  10.1002/pola.24756
• 作为产物：
  描述：

  1,1,3,3,5,5-hexakis(4-(hydroxymethyl)phenoxy)cyclotriphosphazene 在 三溴化磷 作用下， 以 四氢呋喃 为溶剂， 反应 24.0h， 以62%的产率得到1,1,3,3,5,5-hexakis(4-(bromomethyl)phenoxy)cyclotriphosphazene
  参考文献：
  名称：

  通过“点击化学”合成末端封端的A6树枝状聚合物和具有磷腈核的星形聚合物

  摘要：

  新型六臂和pyr（Pyr）封端的磷腈树枝状聚合物[N 3 P 3-（Pyr）6 ]和具有聚（ε-己内酯）（PCL）臂的星形聚合物[N 3 P 3-（PCL- Pyr）通过两个系列的反应制备[ 6 ]。在这些系列中，从六羟基官能磷腈衍生物（N 3 P 3-（OH）6）开始使用了先核方法。在ε-己内酯的开环聚合反应中用作引发剂以制备六臂PCL星型聚合物（N 3 P 3-（PCL- OH）6）。N 3 P 3-（OH）6和N 3 P 3-（PCL- OH）6的羟基官能度随后成功地转化为溴化物和叠氮化物。叠氮化物官能树状大分子前体（N 3 P 3-（N 3）6）和星形聚合物（N 3 P 3-（PCL- N 3）6的进一步端基修饰）是在最后一步通过叠氮化物官能团和1-乙炔基1之间的Cu（I）催化的点击反应定量实现的。此外，the封端的磷腈树枝状聚合物和星形聚合物用于多壁碳纳米管的非共价官能化。©2011

  DOI：

  10.1002/pola.24756

文献信息

• Catalytic Cooperativity, Nuclearity, and O ₂ /H ₂ O ₂ Specificity of Multi‐Copper(II) Complexes of Cyclen‐Tethered Cyclotriphosphazene Ligands in Aqueous Media
  作者：Le Wang、Yong Ye、Vasiliki Lykourinou、Junliang Yang、Alexander Angerhofer、Yufen Zhao、Li‐June Ming

  DOI：10.1002/ejic.201700811

  日期：2017.11.16

  Three ligands L1, L2, and L3 with 2, 4, and 6 1,4,7,10‐tetraazacyclododecane (cyclen) moieties attached to a cyclotriphosphazene core, respectively, were synthesized, and oxidation activities of their CuII complexes were investigated. Aerobic oxidation of catechol by these complexes follows an intramolecular dinuclear pathway with significant cooperativity (i.e., θ ≈ 1.5 out of a maximum of 2 for two

  分别合成了三个分别带有2、4和6个1,4,7,10-四氮杂环十二烷（环）的配体L1，L2和L3，并研究了其Cu II配合物的氧化活性。这些复合物的邻苯二酚有氧氧化遵循分子内双核途径，具有显着的协同作用（即，对于两个潜在的底物结合位点，θ≈1.5，最大值为2）和动力学常数（即，k cat = 17.5×10 –3 s – 1，K m = 2.8毫米，并且每个二铜中心的催化特异性为k cat / K m 12.5 m –1  s –1，非常显着，而不受束缚的Cu II –cycln的催化特异性遵循双分子双核途径，没有明显的协同性（θ = 0.96），并且k值低四倍猫，尽管它们具有类似的双核机制。EPR光谱和弛豫表明Cu II中心的接近，显示出较宽的光谱成分，尤其是在Cu 6 L3中。热力学参数还表明了多铜II的重要性位在氧化催化中。空气是典型的复合物Cu 2 L1的更具体的氧化剂，对儿茶酚底物的催化特异性k
• First Synthesis of “Majoral-Type” Glycodendrimers Bearing Covalently Bound α-<scp>d</scp>-Mannopyranoside Residues onto a Hexachlocyclotriphosphazene Core
  作者：Mohamed Touaibia、René Roy

  DOI：10.1021/jo801850f

  日期：2008.12.5

  A short and efficient strategy for the first synthesis of "Majoral-Type" multivalent glycodendrimers bearing covalently bound alpha-D-mannopyranosides onto a cyclotriphosphazene scaffold assembled using single-step Step Sonogashira and click chemistry is reported. New glycoclusters with valencies ranging from 6 to 18 and different epitope spatial arrangements were obtained. Cross-linking abilities of this series of glycodendrimers were evaluated with the model lectin from Canavalia ensiformis (Concanavalin A). The decameric mannoside 23, built around 19, was shown to be much faster in cross-linking the tetravalent lectin Concanavalin A than the positive control, which is the polysaccharide mannan from yeast. The new glycoconjugates reported may be promising tools as probes or effectors of biological processes involving multivalent carbohydrate-binding proteins.
• Phosphazene-cored star polymer bearing redox-active side groups as a cathode-active material in Li-ion batteries
  作者：Muhammet Aydin、Mesut Gorur、Faruk Yilmaz

  DOI：10.1016/j.reactfunctpolym.2016.02.008

  日期：2016.5

  A new hexa-armed star polymer bearing 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)-pending polymer chains emanating from a phosphazene core (P2) was prepared and used as the cathode material in Li-ion battery assembly. The properties of the assembled battery (BP2) were compared with those of BL2 assembled using its linear counterpart (L2). Their spin concentrations investigated via solution electron spin resonance (ESR) measurements were found to be almost the same. The charge/discharge capacities and energy densities of BP2 were considerably higher than those of BL2. However, they exhibited comparable charge/discharge efficiencies and their discharge capacities dropped to similar percentages of their initial values. (C) 2016 Elsevier B.V. All rights reserved.
• Phosphazene Based Multicentered Naked-Eye Fluorescent Sensor with High Selectivity for Fe³⁺ Ions
  作者：Reyhan Kagit、Mehmet Yildirim、Ozgur Ozay、Serkan Yesilot、Hava Ozay

  DOI：10.1021/ic402783x

  日期：2014.2.17

  A novel on/off fluorescent rhodamine-based hexapodal Fe3+ probe (L) containing a cyclotriphosphazene core was synthesized by an azide-alkyne "click-reaction". The synthesized compounds (1-5 and L) were characterized by FT-IR; H-1, C-13, and P-31 NMR; and MALDI MS spectrometry. The optical sensor features for the Fe3+ complex of L were investigated by UV-vis and fluorescence spectroscopy. The stoichiometry of L-Fe3+ complex was found to be 1:3 (ligand/metal ion), and the detection limit of L was determined as 4.8 mu M (0.27 mg L-1) for Fe3+ ions. The reusability of the sensor was tested by the addition of ethylenediamine to L-Fe3+ complex solutions followed by the addition of Fe3+ solution.
• Synthesis, Characterization, and Activity of Cyclotriphosphazene-Cyclene Conjugates
  作者：Jin-Hui Wang、Cui-Cui Wang、Di Zhang、Cun-Jiang Liu、Yong Ye、Yufen Zhao

  DOI：10.1080/10426507.2012.741159

  日期：2013.1.1

  Two novel cyclotriphosphazene derivatives were synthesized from hexachloro cyclotriphosphzene. Their structures were characterized by H-1, P-31, and C-13 NMR spectroscopy as well as by IR spectroscopy and electrospray ionization-mass spectrometry (ESI-MS). The Zn complex of 4d was effective in hydrolytic DNA cleavage reactions.