(2E,4E)-Octadeca-2,4-dienoyl chloride | 111076-75-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: (2E,4E)-Octadeca-2,4-dienoyl chloride
• 英文别名: Octadecadienoyl chloride
• CAS: 111076-75-6
• 化学式: C₁₈H₃₁ClO
• 分子量: 298.897
• InChiKey: ADEHMEKNRWYDBF-JLXBFWJWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.6
• 重原子数：
  20
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(十八烷氧基)-1,3-丙烷二醇 、 (2E,4E)-Octadeca-2,4-dienoyl chloride 生成 (3-hydroxy-2-octadecoxypropyl) (2E,4E)-octadeca-2,4-dienoate
  参考文献：
  名称：

  TAKEOKA, SHINJI;IWAI, HIDETAKA;OHNO, HIROYUKI;TSUCHIDA, EISHUN, BULL. CHEM. SOC. JAP., 62,(1989) N, C. 102-108

  摘要：

  DOI：
• 作为产物：
  描述：

  肉豆蔻醛 在 氢氧化钾 、 草酰氯 、 sodium hydride 作用下， 以 乙醇 、 苯 为溶剂， 反应 10.0h， 生成 (2E,4E)-Octadeca-2,4-dienoyl chloride
  参考文献：
  名称：

  Banerji, Avijit; Nandi, Gopa, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1988, vol. 27, # 1-12, p. 163 - 165

  摘要：

  DOI：

文献信息

• BETA-1,3-GLUCAN DERIVATIVE AND METHOD FOR PRODUCING BETA-1,3-GLUCAN DERIVATIVE
  申请人：NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY

  公开号：US20150299339A1

  公开（公告）日：2015-10-22

  An object of the present invention is to provide a β-1,3-glucan derivative which is a polymer having β-1,3-glucan as a main chain, and has thermoplasticity and excellent moldability, and a preparation method thereof. That is, the present invention provides a β-1,3-glucan derivative having a structure represented by General Formula (1) as a main chain. (In Formula (1), each of a plurality of R 1 s independently represents a hydrogen atom or —COR 2 , n represents an integer of 1 or greater, and R 2 represents an aliphatic hydrocarbon group or an aromatic hydrocarbon group. In Formula (1), a plurality of the R 1 s may be the same as or different from each other, and at least a part of a plurality of the R 1 s is —COR 2 .)

  本发明的目的是提供一种β-1,3-葡聚糖衍生物，其作为主链具有β-1,3-葡聚糖，并具有热塑性和优异的可塑性，以及其制备方法。也就是说，本发明提供了一种以通式（1）表示结构的β-1,3-葡聚糖衍生物作为主链。（在公式（1）中，多个R1独立地表示氢原子或-COR2，n表示大于等于1的整数，而R2表示脂肪烃基或芳香烃基。在公式（1）中，多个R1可以相同或不同，而多个R1中的至少一部分是-COR2。）
• Novel compounds and compositions useful for producing analgesia
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0132346A1

  公开（公告）日：1985-01-30

  Alkadienamide compounds, and pharmaceutically-acceptable salts thereof, of the formula: wherein X is O or S; R is straight or branched diene having from 11 to 23 carbon atoms; R1 is H, OH, or OCH3; R2 is OH or a short-chain ester; and wherein at least one of R1 and R2 is OH or OCH3. Compositions, useful for producing analgesia in humans or lower animals, comprise a safe and effective amount of: an alkadienamide, pharmaceutically-acceptable salts thereof, or mixtures thereof; and a pharmaceutically-acceptable carrier. Preferably, these alkadienamides are N-vanillyl- alkadienamides. Methods of treatment, comprising administering a safe and effective amount of these alkadienamides, pharmaceutically-acceptable salts thereof, or mixtures thereof, include methods of parenteral, oral, and topical administration.

  式中的烷二烯酰胺化合物及其药学上可接受的盐： 其中 X 是 O 或 S；R 是具有 11 至 23 个碳原子的直链或支链二烯；R1 是 H、OH 或 OCH3；R2 是 OH 或短链酯；R1 和 R2 中至少有一个是 OH 或 OCH3。对人类或低等动物产生镇痛作用的组合物包含安全有效量的：烷二烯酰胺、其药学上可接受的盐或其混合物；以及药学上可接受的载体。这些烷二烯酰胺最好是 N-香草醛烷二烯酰胺。治疗方法包括施用安全有效量的这些烷二烯酰胺、其药学上可接受的盐或其混合物，包括肠外、口服和局部给药方法。
• Glycolipid derivatives and use thereof
  申请人：Chiba Flour Milling Co., Ltd.

  公开号：EP0861848A1

  公开（公告）日：1998-09-02

  Disclosed are (1) a glycolipid derivative in which a nitrogen atom-containing hydrophobic group is introduced into an anomer carbon atom of a reducing end group of an oligosaccharide having a saccharide polymerization degree of 5 to 30, and (2) a phospholipid vesicle stabilizer comprising a glycolipid derivative in which a nitrogen atom-containing hydrophobic group is introduced into an anomer carbon atom of a reducing end group of an oligosaccharide having a saccharide polymerization degree of 2 to 30.

  公开了（1）一种糖脂衍生物，其中含氮原子的疏水基团被引入糖聚合度为 5 至 30 的寡糖的还原端基的同分异构体碳原子中；以及（2）一种磷脂囊泡稳定剂，它包含一种糖脂衍生物，其中含氮原子的疏水基团被引入糖聚合度为 2 至 30 的寡糖的还原端基的同分异构体碳原子中。
• beta-1,3-GLUCAN DERIVATIVE AND METHOD FOR PRODUCING beta-1,3-GLUCAN DERIVATIVE
  申请人：National Institute Of Advanced Industrial Science

  公开号：EP2921504A1

  公开（公告）日：2015-09-23

  An object of the present invention is to provide a β-1,3-glucan derivative which is a polymer having β-1,3-glucan as a main chain, and has thermoplasticity and excellent moldability, and a preparation method thereof. That is, the present invention provides a β-1,3-glucan derivative having a structure represented by General Formula (1) as a main chain. (In Formula (1), each of a plurality of R1s independently represents a hydrogen atom or -COR2, n represents an integer of 1 or greater, and R2 represents an aliphatic hydrocarbon group or an aromatic hydrocarbon group. In Formula (1), a plurality of the R1s may be the same as or different from each other, and at least a part of a plurality of the R1s is -COR2.)

  本发明的目的是提供一种β-1,3-葡聚糖衍生物，它是一种以β-1,3-葡聚糖为主链的聚合物，具有热可塑性和优异的成型性，并提供其制备方法。也就是说，本发明提供了一种以通式（1）表示的结构作为主链的β-1,3-葡聚糖衍生物。 (在式（1）中，多个 R1s 中的每一个独立地代表氢原子或-COR2，n 代表 1 或更大的整数，R2 代表脂肪族烃基或芳香族烃基。在式 (1) 中，多个 R1s 可以彼此相同或不同，且多个 R1s 中至少有一部分是-COR2)。
• Substituted pyrimidine amides of oleic or linoleic acid as inhibitors of acyl-coa cholesterol acyltransferase
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP0245687B1

  公开（公告）日：1991-02-27