1-Hexylamino-anthrachinon | 7567-77-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1-Hexylamino-anthrachinon
• 英文别名: 1-(Hexylamino)anthracene-9,10-dione
• CAS: 7567-77-3
• 化学式: C₂₀H₂₁NO₂
• 分子量: 307.392
• InChiKey: RCPPSOALBUBVLK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  46.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-Hexylamino-anthrachinon 、 β-环糊精 以 甲醇 、 水 为溶剂， 反应 0.33h， 生成
  参考文献：
  名称：

  Sensitive fluorescent vesicles based on the supramolecular inclusion of β-cyclodextrins withN-alkylamino-l-anthraquinone

  摘要：

  Self-assembly fluorescent vesicles were designed and prepared based on the supramolecular interaction of cyclodextrins and N-alkylamino-l-anthraquinone (n-AQ). As the guest molecules, n-AQs with alkyl lengths ranging from C0 to C18 were synthesised by the direct reaction of alkylamine with l-nitroanthraquinone in N,N-dimethylformamide. Transmission electron microscopy (TEM), scanning electron microscopy, dynamic light scattering and epi fluorescence microscopy were employed to study the vesicle system in detail. The formation mechanism of the vesicles was suggested based on the results of TEM observation, UV spectrum, fluorescence spectrum, 1H NMR and simulation in the software Materials 4.3. The fluorescent vesicles show sensitive and multi-responsive properties to external stimuli. Based on these properties, we tried to use the vesicle as a new kind of fluorescence staining material for living cells. The vesicles can effectively stain the human breast cancer cells (MCF-7) and mice mononuclear macrophages (REW-264.7). This paper provides a better understanding in the design and preparation of drug delivery, biomaterials and intelligent materials.

  DOI：

  10.1080/10610278.2010.514614
• 作为产物：
  描述：

  正己胺 、 1-硝基蒽醌 以 N,N-二甲基甲酰胺 为溶剂， 反应 10.0h， 生成 1-Hexylamino-anthrachinon
  参考文献：
  名称：

  Sensitive fluorescent vesicles based on the supramolecular inclusion of β-cyclodextrins withN-alkylamino-l-anthraquinone

  摘要：

  Self-assembly fluorescent vesicles were designed and prepared based on the supramolecular interaction of cyclodextrins and N-alkylamino-l-anthraquinone (n-AQ). As the guest molecules, n-AQs with alkyl lengths ranging from C0 to C18 were synthesised by the direct reaction of alkylamine with l-nitroanthraquinone in N,N-dimethylformamide. Transmission electron microscopy (TEM), scanning electron microscopy, dynamic light scattering and epi fluorescence microscopy were employed to study the vesicle system in detail. The formation mechanism of the vesicles was suggested based on the results of TEM observation, UV spectrum, fluorescence spectrum, 1H NMR and simulation in the software Materials 4.3. The fluorescent vesicles show sensitive and multi-responsive properties to external stimuli. Based on these properties, we tried to use the vesicle as a new kind of fluorescence staining material for living cells. The vesicles can effectively stain the human breast cancer cells (MCF-7) and mice mononuclear macrophages (REW-264.7). This paper provides a better understanding in the design and preparation of drug delivery, biomaterials and intelligent materials.

  DOI：

  10.1080/10610278.2010.514614

文献信息

• Coloured Particles for Electrophoretic Displays
  申请人：Fontana Margherita

  公开号：US20090296195A1

  公开（公告）日：2009-12-03

  The present invention discloses the use of functionalized particles as electrophoretic displaying particles, wherein the functionalized particles are SiO 2 , Al 2 O 3 or mixed SiO 2 and Al 2 O 3 particles comprising, covalently bound to an oxygen atom on the surface, a radical of formula (1), wherein R 1 and R 2 are independently of each other hydrogen, particle surface-O—, or a substituent, n is 1, 2, 3, 4, 5, 6, 7 or 8, B is the direct bond or a bridge member, and D is the residue of an organic chromophore.

  本发明揭示了功能化颗粒作为电泳显示颗粒的用途，其中功能化颗粒为SiO2、Al2O3或混合SiO2和Al2O3颗粒，其中这些颗粒通过共价键结合到表面上的氧原子，具有以下结构的自由基（1），其中R1和R2分别独立地为氢、颗粒表面-O-，或取代基，n为1、2、3、4、5、6、7或8，B为直接键或桥接成员，D为有机色团的残基。
• COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS
  申请人：BASF SE

  公开号：EP1948738B1

  公开（公告）日：2018-02-28
• US8456733B2
  申请人：——

  公开号：US8456733B2

  公开（公告）日：2013-06-04
• [EN] COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS<br/>[FR] C09C 1/30 TITLE: PARTICULES COLOREES POUR AFFICHAGES ELECTROPHORETIQUES
  申请人：CIBA SC HOLDING AG

  公开号：WO2007048721A1

  公开（公告）日：2007-05-03

  [EN] The present invention discloses the use of functionalized particles as electrophoretic displaying particles, wherein the functionalized particles are SiO₂, Al₂O₃ or mixed SiO₂ and Al₂O₃ particles comprising, covalently bound to an oxygen atom on the surface, a radical of formula (1), wherein R₁ and R₂ are independently of each other hydrogen, particle surface-O-, or a substituent, n is 1, 2, 3, 4, 5, 6, 7 or 8, B is the direct bond or a bridge member, and D is the residue of an organic chromophore.
  [FR] La présente invention concerne l'utilisation de particules fonctionnalisées en tant que particules d'affichages électrophorétiques, lesdites particules fonctionnalisées étant des particules de SiO₂, de Al₂O₃ ou d'un mélange de SiO₂ et de Al₂O₃ comprenant, lié de manière covalente à un atome d'oxygène à la surface, un radical de formule (1), dans laquelle R₁ et R₂ représentent indépendamment l'un de l'autre l'hydrogène, un -O- de surface de particule ou un substituant, n vaut 1, 2, 3, 4, 5, 6, 7 ou 8, B représente une liaison directe ou un élément ponté et D représente le résidu d'un chromophore organique.
• Sensitive fluorescent vesicles based on the supramolecular inclusion of β-cyclodextrins with<i>N</i>-alkylamino-<scp>l</scp>-anthraquinone
  作者：Tao Sun、Huacheng Zhang、Hui Yan、Jianye Li、Guanghui Cheng、Aiyou Hao、Hongwei Qiao、Feifei Xin

  DOI：10.1080/10610278.2010.514614

  日期：2011.5.1

  Self-assembly fluorescent vesicles were designed and prepared based on the supramolecular interaction of cyclodextrins and N-alkylamino-l-anthraquinone (n-AQ). As the guest molecules, n-AQs with alkyl lengths ranging from C0 to C18 were synthesised by the direct reaction of alkylamine with l-nitroanthraquinone in N,N-dimethylformamide. Transmission electron microscopy (TEM), scanning electron microscopy, dynamic light scattering and epi fluorescence microscopy were employed to study the vesicle system in detail. The formation mechanism of the vesicles was suggested based on the results of TEM observation, UV spectrum, fluorescence spectrum, 1H NMR and simulation in the software Materials 4.3. The fluorescent vesicles show sensitive and multi-responsive properties to external stimuli. Based on these properties, we tried to use the vesicle as a new kind of fluorescence staining material for living cells. The vesicles can effectively stain the human breast cancer cells (MCF-7) and mice mononuclear macrophages (REW-264.7). This paper provides a better understanding in the design and preparation of drug delivery, biomaterials and intelligent materials.