palmitic acid stearic acid-anhydride | 119369-47-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: palmitic acid stearic acid-anhydride
• 英文别名: Palmitinsaeure-stearinsaeure-anhydrid；Stearic-palmitic anhydride；hexadecanoyl octadecanoate
• CAS: 119369-47-0
• 化学式: C₃₄H₆₆O₃
• 分子量: 522.896
• InChiKey: NDEKYMCHIRKMFT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  15.6
• 重原子数：
  37
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  棕榈酸 、 十八烷酰氯 100.0 ℃ 、266.64 Pa 条件下， 生成 palmitic acid stearic acid-anhydride
  参考文献：
  名称：

  Youngs, Journal of the American Oil Chemists' Society, 1958, vol. 35, p. 416

  摘要：

  DOI：

文献信息

• [EN] LIPIDS THAT INCREASE INSULIN SENSITIVITY AND METHODS OF USING THE SAME<br/>[FR] LIPIDES AUGMENTANT LA SENSIBILITÉ À L'INSULINE ET LEURS PROCÉDÉS D'UTILISATION
  申请人：BETH ISREAL DEACONESS MEDICAL CT INC

  公开号：WO2013166431A1

  公开（公告）日：2013-11-07

  The invention provides, inter alia, fatty acyl hydroxy fatty acid (FAHFA; a novel class of estolide-related molecules) and diagnostic and treatment methods for a variety of disorders- including diabetes-related disorders, Metabolic Syndrome, polycyctic ovarian syndrome, cancer, and inflammatory disorders— using them; as well as methods of screening for additional compounds that are useful in treating these disorders and/or that modulate FAHFA levels, FAHFA-mediated signaling, and FAHFA-mediated biological effects.

  这项发明提供了脂肪酰羟基脂肪酸（FAHFA；一类新型的酯脂类分子）以及用于治疗各种疾病的诊断和治疗方法，包括与糖尿病相关的疾病、代谢综合征、多囊卵巢综合征、癌症和炎症性疾病，以及使用它们的方法；以及筛选对这些疾病有用或调节FAHFA水平、FAHFA介导的信号传导和FAHFA介导的生物效应的其他化合物的方法。
• [EN] NEW NON-IONIC SURFACTANTS FOR SOLUBILIZING POORLY SOLUBLE MOLECULES<br/>[FR] NOUVEAUX TENSIOACTIFS NON IONIQUES DESTINES A SOLUBILISER DES MOLECULES FAIBLEMENT SOLUBLES
  申请人：ASTRAZENECA AB

  公开号：WO2004089869A1

  公开（公告）日：2004-10-21

  New non-ionic surfactants in the form of polyoxyalkylene glycol hydroxy fatty acid derivatives or monoalkylated polyoxyalkylene glycol hydroxy fatty acid derivatives having a polyoxyalkylene / alkyl polyoxyalkylene chain with a chain-length of 25 - 455 repeating units and a specified substituent on the hydroxy position of the specified hydroxy fatty acid, according to the general formula (I) CH3 - (CH2)x - CH - (CH2)y - CO - [-O - R3 - ]z - O - R1 R2 - O (I); wherein for example R1 is methyl, R2 is optionally substituted C14 - C22 acyl, alkyl, or alkenyl, R3 is ethylene, x is 2-12, y is 7-17, (x + y) is 3-19 and z is 25-57; advantageously prepared by involving an enzymatic process, formulations comprising them, their use as solubilizers and a process involving a hydrolytic enzyme for preparing them.

  新的非离子表面活性剂以聚氧烷基乙二醇羟基脂肪酸衍生物或单烷基化聚氧烷基乙二醇羟基脂肪酸衍生物的形式存在，具有聚氧烷基/烷基聚氧烷基链，链长为25-455个重复单元，并且在指定的羟基脂肪酸的羟基位置上具有特定的取代基，根据通式（I）CH3 -（CH2）x - CH -（CH2）y - CO - [-O - R3 -]z - O - R1 R2 - O（I）；例如，其中R1为甲基，R2为可选的取代的C14 - C22酰基、烷基或烯基，R3为乙烯基，x为2-12，y为7-17，（x + y）为3-19，z为25-57；通过涉及酶过程有利地制备，包含它们的配方，它们作为溶剂的用途以及涉及水解酶制备它们的过程。
• [EN] ESTER FORMATION OF FATTY ACID AND HYDROXYCARBOXYLIC AID<br/>[FR] FORMATION D'ESTER D'ACIDE GRAS ET D'ACIDE HYDROXYCARBOXYLIQUE
  申请人：PURAC BIOCHEM BV

  公开号：WO2013189853A1

  公开（公告）日：2013-12-27

  The present invention relates to a process for the transesterification of a fatty acid ester of a lower alcohol and a salt of hydroxycarboxylic acid without making use of organic solvents. The process can also be carried out without added anionic surface active agents.

  本发明涉及一种不使用有机溶剂的脂肪酸酯和羟基羧酸盐的酯交换过程。该过程也可以在不添加阴离子表面活性剂的情况下进行。
• Non-ionic surfactants for solubilizing poorly solubule molecules
  申请人：von Corswant Christian

  公开号：US20060287542A1

  公开（公告）日：2006-12-21

  New non-ionic surfactants in the form of polyoxyalkylene glycol hydroxy fatty acid derivatives or monoalkylated polyoxyalkylene glycol hydroxy fatty acid derivatives having a polyoxyalkylene / alkyl polyoxyalkylene chain with a chain-length of 25-455 repeating units and a specified substituent on the hydroxy position of the specified hydroxy fatty acid, according to the general formula (I) CH 3 —(CH 2 ) x —CH—(CH 2 ) y —CO—[—O—R 3 —] z —O—R 1 R 2 —O (I); wherein for example R 1 is methyl, R 2 is optionally substituted C 14 —C 22 acyl, alkyl, or alkenyl, R 3 is ethylene, x is 2-12, y is 7-17, (x+y) is 3-19 and z is 25-57; advantageously prepared by involving an enzymatic process, formulations comprising them, their use as solubilizers and a process involving a hydrolytic enzyme for preparing them.

  新的非离子表面活性剂采用聚氧烷基乙二醇羟基脂肪酸衍生物或单烷基化聚氧烷基乙二醇羟基脂肪酸衍生物形式，具有聚氧烷基/烷基聚氧烷基链，链长为25-455个重复单元，并且在指定羟基脂肪酸的羟基位置上具有指定的取代基，按照通式(I) CH3—(CH2)x—CH—(CH2)y—CO—[—O—R3—]z—O—R1R2—O (I)；其中，例如R1为甲基，R2为可选取代的C14-C22酰基，烷基或烯基，R3为乙烯，x为2-12，y为7-17，(x+y)为3-19，z为25-57；通过涉及酶法的方法优选制备，包含它们的配方，它们作为溶解剂的用途以及涉及水解酶制备它们的方法。
• Stabilized, high solids, coal-oil mixtures and methods for the production thereof
  申请人：GULF AND WESTERN INDUSTRIES, INC.

  公开号：EP0105236A2

  公开（公告）日：1984-04-11

  Stabilized high solids content coal-oil mixtures are provided by the admixture of coal and oil in the presence of a saturated or unsaturated fatty acid and a gelforming agent under selected conditions of admixture.

  稳定的高固体含量煤油混合物是在选定的混合条件下，在饱和或不饱和脂肪酸和胶凝剂的存在下将煤和油混合而成的。