1-(2-methoxyethoxy)-2,5-dimethylbenzene | 98684-36-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-(2-methoxyethoxy)-2,5-dimethylbenzene
• 英文别名: 2-(2-Methoxyethoxy)-1,4-dimethylbenzene
• CAS: 98684-36-7
• 化学式: C₁₁H₁₆O₂
• mdl: MFCD23714653
• 分子量: 180.247
• InChiKey: ZCLGAZJQNQNTMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  间甲酚 、 alkaline earth salt of/the/ methylsulfuric acid 在 正丁基锂 、 sodium hydride 作用下， 以 乙醚 、 N,N-二甲基甲酰胺 为溶剂， 反应 17.5h， 生成 1-(2-methoxyethoxy)-2,5-dimethylbenzene
  参考文献：
  名称：

  Wada, Akimori; Kanatomo, Shoichi; Nagai, Sotoo, Chemical and pharmaceutical bulletin, 1985, vol. 33, # 3, p. 1016 - 1022

  摘要：

  DOI：

文献信息

• POLYMER COMPOUND AND COMPOSITION CONTAINING THE SAME
  申请人：Mikami Satoshi

  公开号：US20100033086A1

  公开（公告）日：2010-02-11

  A polymer compound comprising as repeating units an optionally substituted fluorenediyl group and a phenylene group having one or more substituents, and comprising a repeating unit of the following formula (1) and/or a group of the following formula (2): (in the formula (1), Ar 1 and Ar 2 represent an arylene group or di-valent aromatic heterocyclic group, and Ar 1 and may be the same or different.) (in the formula (2), Ar 1 represents the same meaning as described above. Ar 3 represents an aryl group or mono-valent aromatic heterocyclic group.).

  一种聚合物化合物，其重复单元包括一个可选取代的芴基基团和一个具有一个或多个取代基的苯基团，并包括以下式(1)的重复单元和/或以下式(2)的基团： （在式（1）中，Ar1和Ar2表示芳烃基团或双价芳香杂环基团，Ar1和Ar2可以相同或不同。） （在式（2）中，Ar1表示与上述相同的含义。Ar3表示芳基团或单价芳香杂环基团。）
• WADA, AKIMORI;KANATOMO, SHOICHI;NAGAI, SOTOO, CHEM. AND PHARM. BULL., 1985, 33, N 3, 1016-1022
  作者：WADA, AKIMORI、KANATOMO, SHOICHI、NAGAI, SOTOO

  DOI：——

  日期：——
• SUBSTITUTED 4,5,6,7-TETRAHYDRO-PYRAZOLO[1,5-a]PYRAZINE DERIVATIVES AND 5,6,7,8-TETRAHYDRO-4H-PYRAZOLO[1,5-a][1,4]DIAZEPINE DERIVATIVES AS ROS1 INHIBITORS
  申请人：Janssen Pharmaceutica NV

  公开号：US20170174690A1

  公开（公告）日：2017-06-22

  The present invention relates to substituted 4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyrazine derivatives and 5,6,7,8-tetrahydro-4H-pyrazolo[1,5-a][1,4]diazepine derivatives of formula (I) wherein the variables have the meaning defined in the claims. The compounds according to the present invention are useful as ROS1 inhibitors. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.
• US7465748B2
  申请人：——

  公开号：US7465748B2

  公开（公告）日：2008-12-16
• Wada, Akimori; Kanatomo, Shoichi; Nagai, Sotoo, Chemical and pharmaceutical bulletin, 1985, vol. 33, # 3, p. 1016 - 1022
  作者：Wada, Akimori、Kanatomo, Shoichi、Nagai, Sotoo

  DOI：——

  日期：——