3,4-dideoxy-erythro-hexitol | 204120-45-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,4-dideoxy-erythro-hexitol
• 英文别名: (2R,5R)-hexane-1,2,5,6-tetrol
• CAS: 204120-45-6
• 化学式: C₆H₁₄O₄
• 分子量: 150.175
• InChiKey: AMXRXGOSEWMPEF-PHDIDXHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.7
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  80.9
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3,4-dideoxy-erythro-hexitol 生成 meso-1,2,5,6-tetrahydroxyhexane
  参考文献：
  名称：

  URBAS, BRANKO

  摘要：

  DOI：
• 作为产物：
  描述：

  1,6-diacetyl-3,4-dideoxy-erythro-hex-E-3-enitol 在 palladium on activated charcoal 吡啶 、 sodium methylate 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 3.33h， 生成 3,4-dideoxy-erythro-hexitol
  参考文献：
  名称：

  Synthesis of 1,2:5,6-dianhydro-3,4-dideoxy-erythro- and D-threo-hexitol and their E-3-ENE derivatives

  摘要：

  DOI：

  10.1016/s0008-6215(00)85364-1

文献信息

• Optical active compound and liquid crystal composition
  申请人：MITSUBISHI RAYON CO., LTD.

  公开号：EP0396410A2

  公开（公告）日：1990-11-07

  Disclosed is an optically active compound represented by the formula: or .wherein R* represents (k = 1 - 14, X1 is direct bond or -0-, *C is an asymmetric carbon), R is linear alkyl, optically active monohalogenoalkyl or optically active alkyl with CH3 branch, X is direct bond, -0-, -C02- or -OCO-, Y is direct bond, -OCO-, -C02-, -CH20- or -OCH2-, A1 and (B is H, halo or cyano), m = 0 or 1, n = 1 - 14, Z1 is -C02- or -CH20-, and Z2 is -CO2-, -CH2O- or -O-, with the proviso that when m = 0 in formula (2), A3 is and when Y is direct bond and Z2 is -0- in formula (2), combination of A3 and A4 is neither combination of nor combination of This compound is used as a ferroelectric liquid crystal or an additive to be incorporated with a ferroelectric liquid crystal or a non-ferroelectric liquid crystal of SmC phase.

  本发明公开了一种光学活性化合物，其分子式为 或 其中 R* 代表 (k＝1-14，X1为直接键或-0-，*C为不对称碳)，R为直链烷基、光学活性单卤代烷基或具有CH3支链的光学活性烷基，X为直接键、-0-、-C02-或-OCO-，Y为直接键、-OCO-、-C02-、-CH20-或-OCH2-，A1和... (B 是 H、卤代或氰基），m = 0 或 1，n = 1 - 14，Z1 是 -C02- 或 -CH20-，Z2 是 -CO2-、-CH2O- 或 -O-，但当式（2）中 m = 0 时，A3 是 而当式（2）中 Y 为直接键且 Z2 为-0-时，A3 和 A4 的组合既不是-C02-、-CH20-或-O-的组合，也不是-C02-、-CH2O-或-O-的组合。 的组合，也不是 该化合物可用作铁电液晶或添加剂，与 SmC 相的铁电液晶或非铁电液晶结合使用。
• Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same
  申请人：Daiso Co., Ltd.

  公开号：EP0439129A2

  公开（公告）日：1991-07-31

  The present invention relates to novel optically active isoxazole derivatives represented by general formula: which are useful as intermediates for synthesis of prostaglandin and a process for producing the same as well as novel aldehyde compounds represented by general formula: which are intermediates for preparing the compounds [XI] described above and a process for preparation thereof. In the compounds shown by these formulae, R¹ represents an alkyl group or a cycloalkyl group which may have an alkoxy group or a group shown by -Ra-A-B (wherein Ra is an alkyl group; A is a hetero atom or an single bond; and B is an aromatic or hetero ring which may have a substituent(s)); and R² and R³, which may be the same or different, each represents an aralkyl group, a silyl group or an acyl group.

  本发明涉及通式所代表的新型光学活性异噁唑衍生物： 的新型光学活性异噁唑衍生物及其制备方法，以及通式： 是制备上述化合物 [XI] 的中间体及其制备方法。在这些通式所示的化合物中，R¹代表烷基或环烷基，环烷基可带有烷氧基或-Ra-A-B所示的基团（其中Ra为烷基；A为杂原子或单键；B为芳香环或杂环，可带有取代基）；R²和R³可相同或不同，各自代表芳烷基、硅烷基或酰基。
• Symmetry-Assisted Synthesis of <i>C</i>₂-Symmetric <i>trans</i>-α,α‘-Bis(hydroxymethyl)pyrrolidine and -piperidine Derivatives via Double Sharpless Asymmetric Dihydroxylation of α,ω-Terminal Dienes
  作者：Hiroki Takahata、Seiki Takahashi、Shin-ichi Kouno、Takefumi Momose

  DOI：10.1021/jo971995f

  日期：1998.4.1

  A new strategy has been developed for the synthesis of C-2-symmetric trans-alpha,alpha'-bis(hydroxymethyl)pyrrolidine and piperidine derivatives 1-3 starting from symmetric alpha,omega-terminal dienes 4-6. The double-asymmetric dihydroxylation (AD) reaction of 4-6 gave C-2-symmetric tetrols, which were converted in a four-step sequence to C-2-symmetric azacycloalkanes 17, 9, and 22, respectively. These azacycloalkanes were transformed into 1-3 in high enantiomeric excess (82% --> 98%ee). The double AD reaction proved to cause enantiomeric enhancement, even though the asymmetric induction for the first AD reaction is moderate. In addition, it was observed that the chromatography on silica gel of several C-2-symmetric azacycloalkanes (17, 20, and 22) of varying ee's resulted in marked enantiomeric fractionation.
• URBAS, BRANKO
  作者：URBAS, BRANKO

  DOI：——

  日期：——
• US5164113A
  申请人：——

  公开号：US5164113A

  公开（公告）日：1992-11-17