4,4'-di(3-thienyl)biphenyl | 1104454-95-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-di(3-thienyl)biphenyl
• 英文别名: 4,4'-bis(3-thienyl)biphenyl；3-[4-(4-Thiophen-3-ylphenyl)phenyl]thiophene；3-[4-(4-thiophen-3-ylphenyl)phenyl]thiophene
• CAS: 1104454-95-6
• 化学式: C₂₀H₁₄S₂
• 分子量: 318.463
• InChiKey: MSEHFUFKKIFCCA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4,4'-di(3-thienyl)biphenyl 在 N-碘代丁二酰亚胺 、 溶剂黄146 作用下， 以 氯仿 为溶剂， 以41%的产率得到4,4'-bis(2-iodo-3-thienyl)biphenyl
  参考文献：
  名称：

  Preparations of bis[2-(2-arylethynyl)-3-thienyl]arenes and bis[2-{2-(trimethylsilyl)ethynyl}-3-thienyl]arenes

  摘要：

  4,4'-Bis[2-(2-phenylethynyl)-3-thienyl]biphenyl, 4,4'-bis[2-[2-(trimethylsilyl)ethynyl}-3-thienyl]biphenyl and their congeners were prepared and their properties were studied. Extension of pi-system through the central benzene ring was suggested by UV-vis spectra. Connection of two 1,4-bis[2-{2-(trimethylsilyl)ethynyl}-3-thienyl]benzene units was exemplified. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.10.088
• 作为产物：
  描述：

  3-噻吩硼酸 、 4,4-二碘联苯 在 四(三苯基膦)钯 、 potassium carbonate 作用下， 以 四氢呋喃 、 水 、 甲苯 为溶剂， 反应 24.0h， 以93%的产率得到4,4'-di(3-thienyl)biphenyl
  参考文献：
  名称：

  Preparations of bis[2-(2-arylethynyl)-3-thienyl]arenes and bis[2-{2-(trimethylsilyl)ethynyl}-3-thienyl]arenes

  摘要：

  4,4'-Bis[2-(2-phenylethynyl)-3-thienyl]biphenyl, 4,4'-bis[2-[2-(trimethylsilyl)ethynyl}-3-thienyl]biphenyl and their congeners were prepared and their properties were studied. Extension of pi-system through the central benzene ring was suggested by UV-vis spectra. Connection of two 1,4-bis[2-{2-(trimethylsilyl)ethynyl}-3-thienyl]benzene units was exemplified. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2008.10.088

文献信息

• Chemistry of Bis(2-ethynyl-3-thienyl)arene and Related Systems, Part 5: Preparation of an Unsymmetrical 4,4’-Bis(3-thienyl)biphenyl Derivative Containing a 2-[2-(Diphenylphosphino)ethynyl]-3-thienyl Moiety
  作者：Kozo Toyota、Yasutomo Tsuji、Noboru Morita

  DOI：10.1080/10426501003772037

  日期：2010.5.27

  An unsymmetrically substituted 4,4′-bis(3-thienyl)biphenyl derivative of 4-(2-ethynyl-3-thienyl)-4′-(3-thienyl)biphenyl type was prepared, utilizing 4-bromo-4′-(2-iodo-3-thienyl) biphenyl as synthetic intermediate. Reaction of 4-(2-ethynyl-3-thienyl)-4′-(3-thienyl) biphenyl with ethylmagnesium bromide followed by treatment with chlorodiphenylphosphine afforded 4-[2-(2-diphenylphosphinoethynyl)-3-t

  利用4-溴-4'-制备了4-(2-乙炔基-3-噻吩基)-4'-(3-噻吩基)联苯型的不对称取代的4,4'-双(3-噻吩基)联苯衍生物。 (2-iodo-3-thienyl) 联苯作为合成中间体。4-(2-乙炔基-3-噻吩基)-4'-(3-噻吩基)联苯与溴化乙基镁反应，然后用氯二苯基膦处理，得到4-[2-(2-二苯基膦基乙炔基)-3-噻吩基]-4' -(3-噻吩基)联苯。