[carboxymethyl-(2-methoxyphenyl)-phenylphosphaniumyl]boranuide | 871517-96-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: [carboxymethyl-(2-methoxyphenyl)-phenylphosphaniumyl]boranuide
• CAS: 871517-96-3
• 化学式: C₁₅H₁₈BO₃P
• 分子量: 288.091
• InChiKey: SLDIRMNUNWQEIK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [carboxymethyl-(2-methoxyphenyl)-phenylphosphaniumyl]boranuide 以 xylene 为溶剂， 生成 (o-anisyl)(methyl)phenylphosphine borane
  参考文献：
  名称：

  Synthesis and reactions of phosphine-boranes. Synthesis of new bidentate ligands with homochiral phosphine centers via optically pure phosphine-boranes

  摘要：

  DOI：

  10.1021/ja00169a036
• 作为产物：
  描述：

  (S(P),1'R,2'S,5'R)-o-anisyl{{((2'-isopropyl-5'-methylcyclohexyl)oxy)carbonyl}methyl}phenylphosphine-borane 在 氢氧化钾 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 生成 [carboxymethyl-(2-methoxyphenyl)-phenylphosphaniumyl]boranuide
  参考文献：
  名称：

  Synthesis and reactions of phosphine-boranes. Synthesis of new bidentate ligands with homochiral phosphine centers via optically pure phosphine-boranes

  摘要：

  DOI：

  10.1021/ja00169a036

文献信息

• Iridium Complexes with Phosphine−Phosphite Ligands. Structural Aspects and Application in the Catalytic Asymmetric Hydrogenation of N-Aryl Imines
  作者：Sergio Vargas、Miguel Rubio、Andrés Suárez、Diego del Río、Eleuterio Álvarez、Antonio Pizzano

  DOI：10.1021/om050885t

  日期：2006.2.1

  A family of modularly designed phosphine-phosphites (P-OP), possessing a C-C-O backbone, has been synthesized and evaluated in the iridium-catalyzed asymmetric hydrogenation of N-aryl imines. The enantioselectivity of this reaction is highly dependent on the nature of the ligand, and catalysts bridged by an oxyethylene fragment have produced significantly higher enantiomeric excesses (Delta ee > 20%) than their o-oxyphenylene counterparts. Structural studies by X-ray crystallography and NMR spectroscopy of complexes with the formulation [Ir(COD)(P-OP)]BF4 and Ir(Cl)(CO)(P-OP), complemented by DFT calculations of model compounds of the chlorocarbonyls, have shown important differences between complexes bridged by an aliphatic or an aromatic bridge, regarding the iridacycle conformation and the location of phosphine substiments. Catalyst optimization has afforded enantioselectivities from 72 to 85% ee in the hydrogenation of several N-aryl imines.
• Synthesis and reactions of phosphine-boranes. Synthesis of new bidentate ligands with homochiral phosphine centers via optically pure phosphine-boranes
  作者：Tsuneo Imamoto、Toshiyuki Oshiki、Takashi Onozawa、Tetsuo Kusumoto、Kazuhiko Sato

  DOI：10.1021/ja00169a036

  日期：1990.6