8H-呋喃并[3,2-g]吲哚 | 863994-90-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 8H-呋喃并[3,2-g]吲哚
• 英文名称: 8H-Furo[3,2-g]indole
• CAS: 863994-90-5
• 化学式: C₁₀H₇NO
• 分子量: 157.17
• InChiKey: BSPXWOWUDWKJLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  28.9
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] ORAL COMPLEMENT FACTOR D INHIBITORS<br/>[FR] INHIBITEURS ORAUX DU FACTEUR D DU COMPLÉMENT
  申请人：BIOCRYST PHARM INC

  公开号：WO2021072198A1

  公开（公告）日：2021-04-15

  Disclosed are compounds of formula (I), and pharmaceutically acceptable salts thereof, which are inhibitors of the complement system. Also provided are pharmaceutical compositions comprising such a compound, and methods of using the compounds and compositions in the treatment or prevention of a disease or condition characterized by aberrant complement system activity.

  揭示了式(I)的化合物及其药学上可接受的盐，这些化合物是裂解系统的抑制剂。还提供了包含这种化合物的药物组合物，以及使用这些化合物和组合物治疗或预防由异常裂解系统活性特征的疾病或状况的方法。
• Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
  申请人：Glenn Wayne Robert

  公开号：US20050193504A1

  公开（公告）日：2005-09-08

  Tricyclic 5-6-5 heteroaromatic keratin dyeing compounds having two heteroatoms. Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and one or more tricyclic 5-6-5 heteroaromatic keratin dyeing compounds having two heteroatoms. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.

  三环5-6-5杂环角蛋白染料化合物具有两个杂原子。用于角蛋白纤维氧化染色的组合物，包括适用于染色的介质和一个或多个具有两个杂原子的三环5-6-5杂环角蛋白染料化合物。一种用于氧化染色的角蛋白纤维的方法，包括在氧化剂的存在下施用这样的组合物，以发展所需的着色。
• KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF
  申请人：The Procter and Gamble Company

  公开号：EP1720615A1

  公开（公告）日：2006-11-15
• COSMETIC HAIR DYEING COMPOSITIONS CONTAINING THEM AND USE THEREOF
  申请人：The Procter and Gamble Company

  公开号：EP1720615B1

  公开（公告）日：2009-12-30
• Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof
  申请人：Glenn Robert Wayne

  公开号：US20080134450A1

  公开（公告）日：2008-06-12

  Tricyclic 5-6-5 heteroaromatic keratin dyeing compounds having two heteroatoms. Compositions for the oxidative dyeing of keratin fibers, comprising a medium suitable for dyeing and one or more tricyclic 5-6-5 heteroaromatic keratin dyeing compounds having two heteroatoms. A method for oxidative dyeing of keratin fibers, comprising applying such compositions in the presence of an oxidizing agent, for a period sufficient to develop the desired coloration.