9-十七碳烯酸 | 76261-97-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 9-十七碳烯酸
• 英文名称: 9-Heptadecenoic acid
• 英文别名: trans-9-Heptadecensaeure；heptadec-9t-enoic acid；Heptadec-9t-ensaeure；(E)-heptadec-9-enoic acid
• CAS: 76261-97-7
• 化学式: C₁₇H₃₂O₂
• 分子量: 268.44
• InChiKey: QSBYPNXLFMSGKH-CMDGGOBGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  19
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  9-十七碳烯酸 、 2,6-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-(2-aminoethyl)phenol 在 4-二甲氨基吡啶 、 N,N'-羰基二咪唑 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 生成
  参考文献：
  名称：

  Metallo-Cubosomes：用于治疗性核苷酸递送的锌功能化立方纳米颗粒。

  摘要：

  对于RNA治疗剂的临床应用而言，开发有效且有效的RNA递送系统仍然是一个挑战。在这里，我们描述了从自组装的双连续立方溶致液晶相衍生的RNA传递平台的发展，用锌配位脂质进行功能化。这些金属立方脂质体是由一系列与单油酸甘油酯（GMO）混合的新型脂质锌（II）-双（二甲基吡啶胺）（Zn2BDPA））复合物制备的。金属锌小体通过Zn2BDPA和RNA分子的磷酸基团之间的相互作用显示出对siRNA的高亲和力。结合使用动态光散射（DLS），小角度X射线散射（SAXS）和低温透射电子显微镜（cryo-TEM），我们证明了可以将多种Zn2BDPA脂质衍生物装载到GMO cubosomes中，并且Zn2BDPA脂质的引入影响了所得金属-cubosomes的内部立方相转变。这项研究的发现为开发新型的基于非阳离子脂质的包封系统（用于RNA治疗的金属立方体）奠定了基础。

  DOI：

  10.1021/acs.molpharmaceut.8b00890
• 作为产物：
  描述：

  heptadec-9t-enoic acid ethyl ester 生成 9-十七碳烯酸
  参考文献：
  名称：

  239.合成的长链脂族化合物。第四部分 一些甲基取代的油酸

  摘要：

  DOI：

  10.1039/jr9510001087

文献信息

• [EN] ACID CATALYZED OLIGOMERIZATION OF ALKYL ESTERS AND CARBOXYLIC ACIDS<br/>[FR] OLIGOMÉRISATION À CATALYSE ACIDE D'ESTERS D'ALKYLE ET D'ACIDES CARBOXYLIQUES
  申请人：ELEVANCE RENEWABLE SCIENCES

  公开号：WO2014153406A1

  公开（公告）日：2014-09-25

  The oligomerization of certain carboxylic acids and alkyl esters derived from natural oils is disclosed. This includes the oligomerization of C10-17 unsaturated carboxylic acids such as 9-decenoic acid, where the oligomerization yields a mixture of mono-, di- and tri-carboxylic acids. This also includes the oligomerization of certain alkyl esters, including the oligomerization of C10-17 unsaturated alkyl esters such as methyl 9-decenoate (9-DAME), where the oligomerization yields a mixture of mono-, di- and tri-carboxylic acid esters. Various end use applications for the oligomerized carboxylic acids and oligomerized alkyl esters are also disclosed.

  披露了某些从天然油脂衍生而来的羧酸和烷基酯的寡聚。这包括C10-17不饱和羧酸如9-癸烯酸的寡聚，其中寡聚产生了单羧酸、二羧酸和三羧酸的混合物。这也包括某些烷基酯的寡聚，包括C10-17不饱和烷基酯如甲基9-癸烯酸酯（9-DAME）的寡聚，其中寡聚产生了单羧酸酯、二羧酸酯和三羧酸酯的混合物。还披露了寡聚羧酸和寡聚烷基酯的各种最终用途应用。
• [EN] ESTERAMINES AND DERIVATIVES FROM NATURAL OIL METATHESIS<br/>[FR] ESTERAMINES ET DÉRIVÉS DE MÉTATHÈSE D'HUILE NATURELLE
  申请人：STEPAN CO

  公开号：WO2012061093A1

  公开（公告）日：2012-05-10

  Esteramine compositions and their derivatives are disclosed. The esteramines comprise a reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a tertiary alkanolamine. Derivatives made by quaternizing, sulfonating, alkoxylating, sulfating, and/or sulfitating the esteramines are also disclosed. In one aspect, the ester derivative of the C10-C17 monounsaturated acid or octadecene-1,18-dioic acid is a lower alkyl ester. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin. The esteramines and derivatives are valuable for a wide variety of end uses, including cleaners, fabric treatment, hair conditioning, personal care (liquid cleansing products, conditioning bars, oral care products), antimicrobial compositions, agricultural uses, and oil field applications.

  本文公开了Esteramine组合物及其衍生物。Esteramine包括一种由交换反应得到的C10-C17单不饱和酸、十八烯-1,18-二羧酸或其酯衍生物与三级脂肪胺的反应产物。本文还公开了通过季铵化、磺化、烷氧基化、硫酸化和/或亚硫酸化Esteramine制备的衍生物。在一方面，C10-C17单不饱和酸或十八烯-1,18-二羧酸的酯衍生物是较低的烷基酯。在其他方面，酯衍生物是通过自交换天然油或通过天然油与烯烃的交叉交换得到的不饱和三酰甘油。Esteramine和衍生物对各种最终用途都有价值，包括清洁剂、织物处理、护发、个人护理（液体清洁产品、护理条、口腔护理产品）、抗菌组合物、农业用途和油田应用。
• UNSATURATED FATTY ALCOHOL COMPOSITIONS AND DERIVATIVES FROM NATURAL OIL METATHESIS
  申请人：Di Biase Stephen A.

  公开号：US20130281688A1

  公开（公告）日：2013-10-24

  Unsaturated alcohol compositions are obtained by reducing a metathesis-derived hydrocarbyl unsaturated ester. Also disclosed is a process for preparing an unsaturated alcohol composition, where a metathesis derived hydrocarbyl carbonyl compound is reacted in the presence of a silane compound, an organic solvent, and a catalyst system prepared from a metallic complex and a reducing agent. This mixture is then hydrolyzed with a metallic base, and then mixed with organic solvent. The resultant mixture is then separated, washed, dried, and/or purified to produce the unsaturated alcohol composition. The unsaturated alcohol derivatives are useful in many end-use applications, including, for example, lubricants, functional fluids, fuels, functional additives for such lubricants, functional fluids and fuels, plasticizers, asphalt additives, friction reducing agents, plastics, and adhesives.

  通过还原来自交换反应的烃基不饱和酯可以获得不饱和醇组分。本发明还公开了一种制备不饱和醇组分的方法，其中在有机溶剂、硅烷化合物和由金属配合物和还原剂制备的催化剂体系的存在下，交换反应得到的烃基羰基化合物被反应。然后，这种混合物与金属碱水解，然后与有机溶剂混合。最终的混合物然后被分离、洗涤、干燥和/或纯化以生产不饱和醇组分。这些不饱和醇衍生物在许多最终用途应用中有用，包括例如润滑剂、功能流体、燃料、用于这种润滑剂、功能流体和燃料的功能添加剂、增塑剂、沥青添加剂、减摩剂、塑料和粘合剂。
• UNSATURATED FATTY ALCOHOL DERIVATIVES FROM NATURAL OIL METATHESIS
  申请人：Stepan Company

  公开号：US20150087521A1

  公开（公告）日：2015-03-26

  Sulfate and sulfonate derivatives of unsaturated fatty alcohols, processes for making them, and methods of using them are disclosed. In one aspect, a monounsaturated fatty alcohol composition is made by reducing a metathesis-derived monounsaturated alkyl ester. The fatty alcohol composition is then converted to a sulfate or sulfonate derivative by one or more of alkoxylation, sulfation, sulfonation, and sulfitation. Of particular interest are the sulfate and ether sulfate derivatives.

  本发明涉及不饱和脂肪醇的硫酸盐和磺酸盐衍生物，其制备方法以及使用方法。在一方面，通过还原一种交换反应得到的单不饱和烷基酯来制备单不饱和脂肪醇组合物。然后，通过烷氧基化、硫酸化、磺化和亚硫酸化中的一种或多种方法将脂肪醇组合物转化为硫酸盐或磺酸盐衍生物。特别感兴趣的是硫酸盐和醚硫酸盐衍生物。
• HYDROXY- AND ALDEHYDE FUNCTIONAL COMPOUNDS
  申请人：Meier Michael A.R.

  公开号：US20110198535A1

  公开（公告）日：2011-08-18

  The invention relates to a method for producing a mixture containing hydroxy- and aldehyde functional compounds by a cross-metathesis reaction of at least one at least monounsaturated fatty acid or at least one at least monounsaturated fatty acid derivative with an olefinic compound having at least one hydroxy group and at least one C—C double bond, in the presence of a metathesis catalyst at a maximum temperature of 180° C.

  本发明涉及一种方法，通过交叉烯烃反应，在至多180°C的最高温度下，将至少一种至少单不饱和脂肪酸或至少一种至少单不饱和脂肪酸衍生物与至少一种具有至少一个羟基和至少一个C-C双键的烯烃化合物在存在烯烃交换催化剂的情况下反应，以产生含有羟基和醛基官能团的混合物。